PHENACETIN-ETHOXY-1-13C
- Product Name
- PHENACETIN-ETHOXY-1-13C
- CAS No.
- 72156-72-0
- Chemical Name
- PHENACETIN-ETHOXY-1-13C
- Synonyms
- PHENACETIN-ETHOXY-1-13C;Phenacetin- oxethyl-1-13C;phenacetin-13c1(ethoxy-1-13c);ACETOPHENETIDIN (ETHOXY-1-13C);P-ACETOPHENETIDIDE-ETHOXY-1-13C;Phenacetin-ethoxy-1-13C;n-(4-ethoxy-1-13c-phenyl)acetamide;PHENACETIN-ETHOXY-1-13C, 98 ATOM % 13C;Acetamide, N-[4-(ethoxy-1-13C)phenyl]-;N-[4-ETHOXYPHENYL]ACETAMIDE (ETHOXY-1-13C)
- CBNumber
- CB8298744
- Molecular Formula
- C10H13NO2
- Formula Weight
- 180.22
- MOL File
- 72156-72-0.mol
PHENACETIN-ETHOXY-1-13C Property
- Melting point:
- 134-136 °C(lit.)
- form
- solid
- CAS Number Unlabeled
- 62-44-2
Safety
- Hazard Codes
- T
- Risk Statements
- 45-46-20/21/22-22
- Safety Statements
- 53-22-36/37/39-45
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H350May cause cancer
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C905
- Product name
- Phenacetin(ethoxy-1-13C)
- Packaging
- 0.1g
- Price
- $790
- Updated
- 2021/12/16
PHENACETIN-ETHOXY-1-13C Chemical Properties,Usage,Production
Uses
Phenacetin-13C is the 13C labeled Phenacetin[1]. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[2][3][4].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Chandrasekharan NV, et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13926-31. DOI:10.1073/pnas.162468699
[3] Xiao-Meng He, et al. Effects of long-term smoking on the activity and mRNA expression of CYP isozymes in rats. J Thorac Dis. 2015 Oct 7(10): 1725–1731. DOI:10.3978/j.issn.2072-1439.2015.10.07
[4] Na Gao, et al. Inhibition of Baicalin on Metabolism of Phenacetin, a Probe of CYP1A2, in Human Liver Microsomes and in Rats. PLoS One. 2014 9(2): e89752. DOI:10.1371/journal.pone.0089752
PHENACETIN-ETHOXY-1-13C Preparation Products And Raw materials
Raw materials
Preparation Products
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