ChemicalBook > CAS DataBase List > DC_05

DC_05

Product Name
DC_05
CAS No.
890643-16-0
Chemical Name
DC_05
Synonyms
DC_05;DC_05 (DC-05);DC_05 >=98% (HPLC);DC-05, 10 mM in DMSO;1-((2-(1H-Indol-3-yl)ethyl)amino)-3-(9H-carbazol-9-yl)propan-2-ol;9H-Carbazole-9-ethanol, α-[[[2-(1H-indol-3-yl)ethyl]amino]methyl]-;DC05,Inhibitor,DNMTs,DNA Methyltransferase,DNA MTases,DC 05,DC-05,inhibit
CBNumber
CB83041398
Molecular Formula
C25H25N3O
Formula Weight
383.5
MOL File
890643-16-0.mol
More
Less

DC_05 Property

Boiling point:
667.5±55.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 12 mg/ml; DMSO: 11 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 0.3 mg/ml
form 
A solid
pka
13.72±0.20(Predicted)
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

ChemScene
Product number
CS-4113
Product name
DC-05
Purity
99.08%
Packaging
5mg
Price
$420
Updated
2021/12/16
AK Scientific
Product number
SYN5082
Product name
DC_05
Packaging
50mg
Price
$530
Updated
2021/12/16
ChemScene
Product number
CS-4113
Product name
DC-05
Purity
99.08%
Packaging
10mg
Price
$600
Updated
2021/12/16
ChemScene
Product number
CS-4113
Product name
DC-05
Purity
99.08%
Packaging
50mg
Price
$1800
Updated
2021/12/16
Crysdot
Product number
CD31000402
Product name
DC_05
Purity
98+%
Packaging
5mg
Price
$243
Updated
2021/12/16
More
Less

DC_05 Chemical Properties,Usage,Production

Uses

DC-05 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC50 and a Kd of 10.3 μM and 1.09 μM, respectively.

IC 50

DNMT1: 1.09 μM (Kd); DNMT1: 10.3 μM (IC50); PRMT1: 37.1 μM (IC50)

References

[1] Chen S, et al. Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening. J Med Chem. 2014 Nov 13;57(21):9028-41. DOI:10.1021/jm501134e

DC_05 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

DC_05 Suppliers

China 53 United Kingdom 1 United States 7 Global 61
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Pharmacodia (Beijing) Co.,Ltd
Tel
+86-400-851-9921
Fax
+86-10-82826195
Email
sales@pharmacodia.com
Country
China
ProdList
2317
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
8011
Advantage
55
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
12475
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Lynnchem
Tel
86-(0)29-85992781 17792393971
Email
info@lynnchem.com
Country
China
ProdList
4587
Advantage
58
Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58

890643-16-0, DC_05Related Search:


  • DC_05
  • DC_05 (DC-05)
  • 9H-Carbazole-9-ethanol, α-[[[2-(1H-indol-3-yl)ethyl]amino]methyl]-
  • DC_05 >=98% (HPLC)
  • DC05,Inhibitor,DNMTs,DNA Methyltransferase,DNA MTases,DC 05,DC-05,inhibit
  • 1-((2-(1H-Indol-3-yl)ethyl)amino)-3-(9H-carbazol-9-yl)propan-2-ol
  • DC-05, 10 mM in DMSO
  • 890643-16-0