ChemicalBook > CAS DataBase List > 2-Bromo-4-hydroxybenzoicacid

2-Bromo-4-hydroxybenzoicacid

Product Name: 2-Bromo-4-hydroxybenzoicacid
CAS No.: 28547-28-6
Chemical Name: 2-Bromo-4-hydroxybenzoicacid
Synonyms: 2-Bromo-4-hydroxybenzoicacid;Benzoic acid, 2-bromo-4-hydroxy-
CBNumber: CB83044339
Molecular Formula: C7H5BrO3
Formula Weight: 217.02
MOL File: 28547-28-6.mol

Less

2-Bromo-4-hydroxybenzoicacid Property

Melting point:: 151 °C
Boiling point:: 366.3±32.0 °C(Predicted)
Density: 1.861±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
form: powder
pka: 3.22±0.10(Predicted)
color: Off-white

Less

Safety

HS Code: 2918999090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

TRC

Product number: B852600
Product name: 2-Bromo-4-hydroxybenzoicacid
Packaging: 10mg
Price: $40
Updated: 2021/12/16

ChemScene

Product number: CS-0037965
Product name: 2-Bromo-4-hydroxybenzoicacid
Purity: 98.84%
Packaging: 250mg
Price: $50
Updated: 2021/12/16

Apolloscientific

Product number: OR400738
Product name: 2-Bromo-4-hydroxybenzoicacid
Purity: 95%
Packaging: 250mg
Price: $80
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2629-9-28
Product name: 2-Bromo-4-hydroxybenzoic acid
Purity: 97%
Packaging: 250mg
Price: $88
Updated: 2021/12/16

ChemScene

Product number: CS-0037965
Product name: 2-Bromo-4-hydroxybenzoicacid
Purity: 98.84%
Packaging: 1g
Price: $123
Updated: 2021/12/16

Less

2-Bromo-4-hydroxybenzoicacid Chemical Properties,Usage,Production

Uses

2-Bromo-4-hydroxybenzoic acid is a bromo derivative of hydroxybenzoic acid, a useful building block. 2-Bromo-4-hydroxybenzoic acid has been used in the preparation of urolithins which interfere with the CYP1B1 protein which is linked with prostate cancer.

Synthesis

22532-60-1

28547-28-6

2-Bromo-4-hydroxybenzaldehyde (1.7 g, 8.46 mmol, 1.0 equiv) was used as starting material and dissolved in 30 mL of 2 M aqueous sodium hydroxide solution. Potassium permanganate (2.7 g, 16.92 mmol, 2.0 equiv) was added in batches under ice bath cooling conditions. The reaction mixture was then slowly warmed to room temperature with continuous stirring for 2 hours. After completion of the reaction, the insoluble impurities were removed by filtration and the filtrate was washed once with dichloromethane. To the filtrate, 2 M aqueous hydrochloric acid was slowly added and the pH was adjusted to 1. The aqueous phase was extracted with ethyl acetate, the organic phases were combined and dried over anhydrous sodium sulfate. The organic phase was concentrated under reduced pressure to give the white solid product 2-bromo-4-hydroxybenzoic acid (1.6 g, 88% yield).

References

[1] Patent: CN107383024, 2017, A. Location in patent: Paragraph 0481

2-Bromo-4-hydroxybenzoicacid Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2-Bromo-4-hydroxybenzoicacid Suppliers

China 39 India 1 United Kingdom 1 United States 3 Global 44

Beijing Eternalchem Co,. Ltd.

Tel: 010-59484199 18611897322
Email: sales@eternalchem.com
Country: China
ProdList: 4383
Advantage: 60

Changzhou Wanyao Biotechnology Co., Ltd.

Tel: 0519-89185693 15312551983
Fax: 0519-89185693
Email: 2410037592@qq.com
Country: China
ProdList: 261
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 0512-0512-52358471 17715136450
Fax: 05125235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 12127
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Zhengzhou Huiju Chemical Co., Ltd.

Tel: 0371-55900031 18137872243
Fax: QQ：2853979815
Email: 2853979815@qq.com
Country: China
ProdList: 9996
Advantage: 55

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Win-Win Chemical CO., Limited

Tel: 0577-64498589 15325081899
Fax: 0577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 1083
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
Advantage: 58

Xinyi Kaiwu Chemical Technology Co., Ltd.

Tel: 0516-0516-88997009 18651776937
Email: 4164357@qq.com
Country: China
ProdList: 3204
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

Win-Win chemical CO., Limited

Tel: +86-0086-577-64498589 +86-15355981851
Fax: 0086-577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 14359
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Wuxi Kehua Biological Technology Co., Ltd.

Tel: 0510-86838766 13636419861
Email: 2258830676@qq.com
Country: China
ProdList: 5044
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Fuxin Pharmaceutical

Tel: +86-021-021-50872116 +8613122107989
Email: contact@fuxinpharm.com
Country: China
ProdList: 10000
Advantage: 58

Birdo (Shanghai) Medical Technology Co., Ltd.

Tel: 021-58099077-8041 18601625411
Email: sales@birdotech.com
Country: China
ProdList: 9764
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
Advantage: 58

Shanghai Ruipu Medical Technology Co., Ltd

Tel: 15895968936
Fax: qq 1018762393
Email: 1018762393@qq.com
Country: China
ProdList: 9999
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Shaanxi Dideu Newmaterial Co., Ltd.

Tel: 029-029-63373950 17392216152
Email: 1050@dideu.com
Country: China
ProdList: 9998
Advantage: 58

Shanghai Jianchao Biotechnology Co., LTD

Tel: 15021035486 18081542813
Email: 1804873256@qq.com
Country: China
ProdList: 6684
Advantage: 58

Anhui Henuo Biotechnology Co., Ltd

Tel: 18455579438
Country: China
ProdList: 16684
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

PharmaBlock Sciences (Nanjing), Inc.

Tel: 4000255188
Email: sales@pharmablock.com
Country: China
ProdList: 7268
Advantage: 58

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126 18736790110;
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 50000
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48457
Advantage: 58

Pushan Industry (Shaanxi) Co., Ltd

Tel: 029-81310890 18165209495
Email: 2929288192@qq.com
Country: China
ProdList: 9729
Advantage: 58

BEIJINGYIWANJINGRUI

Tel: 15866847540
Email: dengyt2000@163.com
Country: China
ProdList: 4100
Advantage: 58

Hubei wei shi reagent group ltd., company

Tel: 027-59101766 13125137661
Email: 2853877621@qq.com
Country: China
ProdList: 7979
Advantage: 58

Hubei Moco Chemical Co., Ltd.

Tel: 18627753421; 18627756402
Fax: QQ：3001051413
Email: 3001051413@qq.com
Country: China
ProdList: 20319
Advantage: 58

Shanghai Ken chemical Technology Co.,ltd

Tel: 02152215958
Email: 47697177@qq.com
Country: China
ProdList: 10011
Advantage: 58

Moxin Chemicals

Tel: +86-17320513646 +8617320513646
Email: anna@molcoo.com
Country: China
ProdList: 10000
Advantage: 58

Suzhou ARTK Medchem Co., Ltd.

Tel: +86-512-68323658 +86-18168183658
Email: sales1@artkmedchem.com
Country: China
ProdList: 39002
Advantage: 58

Aromsyn Co., Ltd.

Tel: +86-0571-85585865 +8613336024896
Email: CB@aromsyn.com
Country: China
ProdList: 19183
Advantage: 58

Shanghai Weiyuan Fine Fluorine Science & Development Co., Ltd

Tel: --
Fax: --
Email: wdchen@ecust.edu.cn
Country: China
ProdList: 3899
Advantage: 74

28547-28-6, 2-Bromo-4-hydroxybenzoicacidRelated Search:

2-Bromo-4-hydroxybenzoicacid

Benzoic acid, 2-bromo-4-hydroxy-

28547-28-6