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Methylamino-PEG4-t-butylester

Product Name
Methylamino-PEG4-t-butylester
CAS No.
1621616-14-5
Chemical Name
Methylamino-PEG4-t-butylester
Synonyms
MeNH-PEG4-COOtBu;CAS_1621616-14-5;Methylamino-PEG4-Boc;MeNH-PEG4-CH2CH2COOtBu;Methylamino-PEG4-t-butylester;Methylamino-PEG5-t-butyl ester;tert-Butyl 5,8,11,14-tetraoxa-2-azaheptadecan-17-oate;4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 1,1-dimethylethyl ester;tert-butyl 3-[2-[2-[2-[2-(methylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoate;MeNH-PEG4-CH2CH2COOtBu/4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 1,1-dimethylethyl ester
CBNumber
CB83048726
Molecular Formula
C16H33NO6
Formula Weight
335.44
MOL File
1621616-14-5.mol
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Methylamino-PEG4-t-butylester Property

Boiling point:
401.7±35.0 °C(Predicted)
Density 
1.015±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
solubility 
Soluble in Water, DMSO, DCM, DMF
pka
9.52±0.10(Predicted)
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22379
Product name
Methylamino-PEG4-t-butylester
Purity
98%
Packaging
250mg
Price
$460
Updated
2021/12/16
Apolloscientific
Product number
BIPG1540
Product name
Methylamino-PEG4-t-butyl ester
Packaging
100mg
Price
$546
Updated
2021/12/16
Activate Scientific
Product number
AS107907
Product name
MeNH-PEG4-CH2CH2COOtBu
Purity
97%
Packaging
1g
Price
$580
Updated
2021/12/16
Acrotein
Product number
B-0654
Product name
MeNH-PEG4-CH2CH2COOtBu
Purity
97%
Packaging
0.5g
Price
$275
Updated
2021/12/16
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Methylamino-PEG4-t-butylester Chemical Properties,Usage,Production

Description

Methylamino-PEG4-t-butyl ester is a PEG linker containing a methylamine group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Methylamino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Methylamino-PEG4-t-butylester Preparation Products And Raw materials

Raw materials

Preparation Products

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Methylamino-PEG4-t-butylester Suppliers

Chengdu Pukang Biotechnology Co., Ltd
Tel
18217049878 19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
463
Advantage
58
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10044
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28774
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
9933
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-55051623 18137891487
Fax
QQ:2853979817
Email
3983243027@qq.com
Country
China
ProdList
9996
Advantage
58
Jiangsu aikang biomedical research and development co., LTD
Tel
025-58859352 17714375163
Email
qzhang@aikonchem.com
Country
China
ProdList
15525
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32469
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
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View Lastest Price from Methylamino-PEG4-t-butylester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
MeNH-PEG4-COOtBu 1621616-14-5
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-27

1621616-14-5, Methylamino-PEG4-t-butylesterRelated Search:


  • Methylamino-PEG4-t-butylester
  • Methylamino-PEG5-t-butyl ester
  • CAS_1621616-14-5
  • MeNH-PEG4-CH2CH2COOtBu
  • Methylamino-PEG4-Boc
  • 4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 1,1-dimethylethyl ester
  • tert-Butyl 5,8,11,14-tetraoxa-2-azaheptadecan-17-oate
  • MeNH-PEG4-COOtBu
  • MeNH-PEG4-CH2CH2COOtBu/4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 1,1-dimethylethyl ester
  • tert-butyl 3-[2-[2-[2-[2-(methylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
  • 1621616-14-5