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2-Nitro-5-phenoxyaniline

Product Name
2-Nitro-5-phenoxyaniline
CAS No.
1552-17-6
Chemical Name
2-Nitro-5-phenoxyaniline
Synonyms
(2-Nitro-6-phenoxyphenyl)amine;Benzenamine, 2-nitro-5-phenoxy-
CBNumber
CB83052550
Molecular Formula
C12H10N2O3
Formula Weight
230.22
MOL File
1552-17-6.mol
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2-Nitro-5-phenoxyaniline Property

Melting point:
148-150 °C
Boiling point:
377.7±22.0 °C(Predicted)
Density 
1.322±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
-1.05±0.25(Predicted)
Appearance
Light yellow to yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0100531
Product name
2-Nitro-5-phenoxyaniline
Purity
>97.0%
Packaging
250mg
Price
$30
Updated
2021/12/16
ChemScene
Product number
CS-0100531
Product name
2-Nitro-5-phenoxyaniline
Purity
>97.0%
Packaging
1g
Price
$119
Updated
2021/12/16
Oakwood
Product number
015692
Product name
2-Nitro-5-phenoxy-phenylamine
Packaging
1g
Price
$185
Updated
2021/12/16
Matrix Scientific
Product number
180257
Product name
(2-Nitro-6-phenoxyphenyl)amine
Packaging
500mg
Price
$240
Updated
2021/12/16
Matrix Scientific
Product number
180257
Product name
(2-Nitro-6-phenoxyphenyl)amine
Packaging
1g
Price
$300
Updated
2021/12/16
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2-Nitro-5-phenoxyaniline Chemical Properties,Usage,Production

Synthesis

1635-61-6

108-95-2

1552-17-6

General steps: 1. Dissolve 2-nitro-5-chloroaniline (6 mmol), phenol (6 mmol) and potassium carbonate (9 mmol or 18 mmol, as appropriate) in dimethylsulfoxide (25 mL) and stir the reaction at 80 °C. The reaction time varied depending on the product: 5a required 5 h, 5b and 5d required 4 h, 5c required 4.35 h, and 5f required 8 h. The reaction was carried out at 80 °C. The reaction time varied depending on the product. After completion of the reaction, the mixture was cooled, poured into water, the precipitate was collected by filtration, dried and recrystallized from alcohol to give the target product 2-nitro-5-phenoxyaniline. 2. Alternative method: 2-nitro-5-chloroaniline (6 mmol), phenol (6 mmol) or the corresponding phenol (3 mmol) and potassium carbonate (9 mmol or 18 mmol, as appropriate) are dissolved in dimethylsulfoxide (25 mL) and subjected to sonication at 80°C. The reaction time varies depending on the product. The reaction time varied depending on the product: 1 h for 3a, b and 5a-d, 6 h for 5e and 2 h for 3c and 5f. After completion of the reaction, the mixture was cooled, poured into water, the precipitate was collected by filtration, dried and recrystallized from alcohol to give the target product 2-nitro-5-phenoxyaniline.

References

[1] Russian Chemical Bulletin, 2015, vol. 64, # 8, p. 1971 - 1974
[2] Izv. Akad. Nauk, Ser. Khim., 2015, # 8, p. 1971 - 1974,4
[3] Journal of Heterocyclic Chemistry, 1997, vol. 34, # 3, p. 745 - 748
[4] Patent: US5162318, 1992, A
[5] Patent: US4034107, 1977, A

2-Nitro-5-phenoxyaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Nitro-5-phenoxyaniline Suppliers

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1552-17-6, 2-Nitro-5-phenoxyanilineRelated Search:


  • Benzenamine, 2-nitro-5-phenoxy-
  • (2-Nitro-6-phenoxyphenyl)amine
  • 1552-17-6