2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide

Product Name: 2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide
CAS No.: 522650-83-5
Chemical Name: 2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide
Synonyms: CS-2302;SW-044248;SW-044248, >98%;SW 044248;SW044248;SW044248 >=98% (HPLC);SW044248, 10 mM in DMSO;SW 044248,Topoisomerase,inhibit,SW-044248,SW044248,Inhibitor;2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide;Butanamide, 2-[(5-ethyl-5H-1,2,4-triazino[5,6-b]indol-3-yl)thio]-N-(2-methoxyphenyl)-;2-(5-Ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)-N-(2-methoxy-phenyl )-butyramide
CBNumber: CB83059120
Molecular Formula: C22H23N5O2S
Formula Weight: 421.52
MOL File: 522650-83-5.mol

More

Less

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide Property

storage temp.: 2-8°C
solubility: DMSO:10.5(Max Conc. mg/mL);24.91(Max Conc. mM)
DMF:5.0(Max Conc. mg/mL);11.86(Max Conc. mM)
Ethanol:1.0(Max Conc. mg/mL);2.37(Max Conc. mM)
form: powder
color: white to beige

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1729
Product name: SW044248
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $95.7
Updated: 2022/05/15

Sigma-Aldrich

Product number: SML1729
Product name: SW044248
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $386
Updated: 2022/05/15

Cayman Chemical

Product number: 23459
Product name: SW044248
Purity: ≥98%
Packaging: 5mg
Price: $63
Updated: 2024/03/01

Cayman Chemical

Product number: 23459
Product name: SW044248
Purity: ≥98%
Packaging: 10mg
Price: $113
Updated: 2024/03/01

Cayman Chemical

Product number: 23459
Product name: SW044248
Purity: ≥98%
Packaging: 25 mg
Price: $219
Updated: 2024/03/01

More

Less

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide Chemical Properties,Usage,Production

Uses

2-((5-Ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-N-(2-methoxyphenyl)butanamide is a useful intermediate for organic synthesis and other chemical processes.

Biochem/physiol Actions

SW044248 is a cell permeable, indolotriazine-based compound that selectively inhibits topoisomerase 1 (Top 1), but not Top 2, catalyzed DNA decatenation in a manner distinct from that of camptothecin (Cat. Nos. 208925 & C9911). SW044248 is shown to exhibit antiproliferation efficacy against a subset of non-small-cell lung cancer (NSCLC) cultures (IC50 <5>10 μM) derived from the same patient as HCC4017.

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide Suppliers

China 55 United States 9 Global 64

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

522650-83-5, 2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamideRelated Search:

2-butylsulfinyl-4-phenyl-6-thiophen-2-ylthieno[5,4-b]pyridin-3-amine 4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide SW076956

SW 044248;SW044248

CS-2302

SW-044248, >98%

2-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-N-(2-methoxyphenyl)butanamide

SW-044248

<br>2-(5-Ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)-N-(2-methoxy-phenyl )-butyramide

Butanamide, 2-[(5-ethyl-5H-1,2,4-triazino[5,6-b]indol-3-yl)thio]-N-(2-methoxyphenyl)-

SW044248 >=98% (HPLC)

SW 044248,Topoisomerase,inhibit,SW-044248,SW044248,Inhibitor

SW044248, 10 mM in DMSO

522650-83-5