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HIV-RT inhibitor 1

Product Name
HIV-RT inhibitor 1
CAS No.
1443460-91-0
Chemical Name
HIV-RT inhibitor 1
Synonyms
HIV-RT inhibitor 1;GSK2838232, 10 mM in DMSO;GSK 2838232,GSK-2838232,Human immunodeficiency virus,GSK2838232,Inhibitor,HIV,inhibit;28-Norlup-18-en-21-one, 3-(3-carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(4-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-, (3β)-;4-(((3ar,5ar,5br,9s,11ar,11br,13as)-3a-((r)-2-((4-chlorobenzyl)(2-(dimethylamino)ethyl)amino)-1-hydroxyethyl)-1-isopropyl-5a,5b,8,8,11a-pentamethyl-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2h-cyclopenta[a]chrysen-9-yl)oxy)-2,2-dimethyl-4-oxobutanoic acid;4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[(1R)-2-{[(4-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino}-1-hydroxyethyl]-5a,5b,8,8,11a-pentamethyl-2-oxo-1-(propan-2-yl)-2H,3H,3aH,4H,5H,5aH,5bH,6H,7H,7aH,8H,9H,10H,11H,11aH,11bH,12H,13H,13aH-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxobutanoic acid
CBNumber
CB83121104
Molecular Formula
C48H73ClN2O6
Formula Weight
809.57
MOL File
1443460-91-0.mol
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HIV-RT inhibitor 1 Property

Boiling point:
817.1±65.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
Store at 0-8 °C
solubility 
DMSO:25.0(Max Conc. mg/mL);30.88(Max Conc. mM)
form 
A crystalline solid
pka
4.48±0.28(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21390
Product name
GSK2838232
Purity
≥95%
Packaging
1mg
Price
$40
Updated
2024/03/01
Cayman Chemical
Product number
21390
Product name
GSK2838232
Purity
≥95%
Packaging
5mg
Price
$177
Updated
2024/03/01
Cayman Chemical
Product number
21390
Product name
GSK2838232
Purity
≥95%
Packaging
10mg
Price
$332
Updated
2024/03/01
Cayman Chemical
Product number
21390
Product name
GSK2838232
Purity
≥95%
Packaging
25mg
Price
$778
Updated
2024/03/01
ChemScene
Product number
CS-5446
Product name
GSK2838232
Purity
99.26%
Packaging
5mg
Price
$420
Updated
2021/12/16
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HIV-RT inhibitor 1 Chemical Properties,Usage,Production

Description

GSK2838232 is a second generation inhibitor of HIV-1 maturation (IC90 = 6.4 nM). It is active against a variety of HIV isolates resistant to bevirimat (PA-457; ).

Uses

GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates, extracted from patent WO/2013090664A1, compound51.

References

[1] Hatcher Mark Andrew, et al. Preparation of betulin derivatives for the treatment of HIV. From PCT Int. Appl. (2013), WO 2013090664 A1 20130620.

HIV-RT inhibitor 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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HIV-RT inhibitor 1 Suppliers

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1443460-91-0, HIV-RT inhibitor 1Related Search:


  • HIV-RT inhibitor 1
  • 28-Norlup-18-en-21-one, 3-(3-carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(4-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-, (3β)-
  • GSK 2838232,GSK-2838232,Human immunodeficiency virus,GSK2838232,Inhibitor,HIV,inhibit
  • 4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[(1R)-2-{[(4-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino}-1-hydroxyethyl]-5a,5b,8,8,11a-pentamethyl-2-oxo-1-(propan-2-yl)-2H,3H,3aH,4H,5H,5aH,5bH,6H,7H,7aH,8H,9H,10H,11H,11aH,11bH,12H,13H,13aH-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxobutanoic acid
  • GSK2838232, 10 mM in DMSO
  • 4-(((3ar,5ar,5br,9s,11ar,11br,13as)-3a-((r)-2-((4-chlorobenzyl)(2-(dimethylamino)ethyl)amino)-1-hydroxyethyl)-1-isopropyl-5a,5b,8,8,11a-pentamethyl-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2h-cyclopenta[a]chrysen-9-yl)oxy)-2,2-dimethyl-4-oxobutanoic acid
  • 1443460-91-0