PF-04929113 (Mesylate)

Product Name
PF-04929113 (Mesylate)
CAS No.
1173111-67-5
Chemical Name
PF-04929113 (Mesylate)
Synonyms
SNX5422 Mesylate;SNX-5422 Mesylate;PF-04929113 (Mesylate);PF-04929113 Mesylate, 10 mM in DMSO;SNX-5422 MESYLATE (PF-04929113 MESYLATE);PF 04929113 Mesylate,PF04929113 Mesylate;SNX-5422 MESYLATE;PF04929113 MESYLATE;SNX5422 MESYLATE;trans-4-((2-Carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)cyclohexyl glycinate methanesulfonate;(1r,4r)-4-((2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)cyclohexyl 2-aminoacetate methanesulfonate
CBNumber
CB83121124
Molecular Formula
C26H34F3N5O7S
Formula Weight
617.64
MOL File
1173111-67-5.mol
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PF-04929113 (Mesylate) Property

storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO:46.85(Max Conc. mg/mL);75.85(Max Conc. mM)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P293785
Product name
PF-04929113(Mesylate)
Packaging
10mg
Price
$385
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611733
Product name
PF-04929113 Mesylate
Packaging
10mg
Price
$460.7
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611733
Product name
PF-04929113 Mesylate
Packaging
50mg
Price
$734.4
Updated
2021/12/16
AK Scientific
Product number
2765DF
Product name
SNX-5422mesylate
Packaging
250mg
Price
$834
Updated
2021/12/16
Ambeed
Product number
A202225
Product name
PF-04929113Mesylate
Purity
98%
Packaging
2mg
Price
$99
Updated
2021/12/16
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PF-04929113 (Mesylate) Chemical Properties,Usage,Production

Uses

PF-04929113 (Mesylate) functions as a potent and selective Hsp90 inhibitor. Substances in the discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents.

in vivo

SNX-5422 (50 mg/kg, p.o.) efficiently inhibits tumor growth of HT-29 human colon tumor xenograft model after administration 3 times a week for 3 weeks (qod × 3/2 × 3)[1]. SNX-5422 (20, 40 mg/kg, p.o.) markedly inhibits multiple myeloma (MM) tumor growth and angiogenesis in mice[2].

IC 50

HSP90: 41 nM (Kd)

PF-04929113 (Mesylate) Preparation Products And Raw materials

Raw materials

Preparation Products

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PF-04929113 (Mesylate) Suppliers

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19906
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9503
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32470
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6312
Advantage
58
Shanghai Luofa Biochemical Technology Co., Ltd.
Tel
021-51111890 15317326293
Email
sales@molnova.com
Country
China
ProdList
4195
Advantage
58

1173111-67-5, PF-04929113 (Mesylate)Related Search:


  • SNX5422 Mesylate
  • SNX-5422 Mesylate
  • SNX-5422 MESYLATE;PF04929113 MESYLATE;SNX5422 MESYLATE
  • PF-04929113 (Mesylate)
  • (1r,4r)-4-((2-carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)cyclohexyl 2-aminoacetate methanesulfonate
  • SNX-5422 MESYLATE (PF-04929113 MESYLATE)
  • trans-4-((2-Carbamoyl-5-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)phenyl)amino)cyclohexyl glycinate methanesulfonate
  • PF 04929113 Mesylate,PF04929113 Mesylate
  • PF-04929113 Mesylate, 10 mM in DMSO
  • 1173111-67-5
  • CH4O3SC25H30F3N5O4
  • C26H34F3N5O7S