HIF-2α-IN-1

Product Name: HIF-2α-IN-1
CAS No.: 1799948-06-3
Chemical Name: HIF-2α-IN-1
Synonyms: HIF-2&HIF-2α-IN-1;HIF-2 Alpha -IN-1;HIF 2α IN 1,HIF2αIN1;HIF-2α-IN-1, 10 mM in DMSO;3-[[(3R)-4-(difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-dioxo-3H-benzothiophen-5-yl]oxy]-5-fluoro-benzonitrile;(R)-3-((4-(difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-dioxido-2,3-dihydrobenzo[b]thiophen-5-yl)oxy)-5-fluorobenzonitrile;Benzonitrile, 3-[[(3R)-4-(difluoromethyl)-2,2-difluoro-2,3-dihydro-3-hydroxy-1,1-dioxidobenzo[b]thien-5-yl]oxy]-5-fluoro-
CBNumber: CB83122343
Molecular Formula: C16H8F5NO4S
Formula Weight: 405.3
MOL File: 1799948-06-3.mol

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HIF-2α-IN-1 Property

Boiling point:: 499.8±45.0 °C(Predicted)
Density: 1.70±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
pka: 9.52±0.40(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-5544
Product name: HIF-2α-IN-1
Purity: 99.92%
Packaging: 5mg
Price: $520
Updated: 2021/12/16

ChemScene

Product number: CS-5544
Product name: HIF-2α-IN-1
Purity: 99.92%
Packaging: 10mg
Price: $880
Updated: 2021/12/16

Crysdot

Product number: CD31002918
Product name: HIF-2α-IN-1
Purity: 98+%
Packaging: 5mg
Price: $243
Updated: 2021/12/16

Crysdot

Product number: CD31002918
Product name: HIF-2α-IN-1
Purity: 98+%
Packaging: 10mg
Price: $347
Updated: 2021/12/16

DC Chemicals

Product number: DC23091
Product name: HIF2α-IN-1
Purity: >98%
Packaging: 10mg
Price: $800
Updated: 2021/12/16

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HIF-2α-IN-1 Chemical Properties,Usage,Production

Uses

HIF-2α-IN-1 is a HIF-2α inhibitor has an IC50 of less than 500 nM in HIF-2α scintillation proximity assay. IC50 value: ＜ 500 nM Target: HIF-2α

References

[1] Bruick Richard Keith, et al. HIF-2α inhibitors for treating iron overload disorders. From PCT Int. Appl. (2016), WO 2016057242 A1 20160414.
[2] Dixon Darryl David, et al. Preparation of cyclic sulfone and sulfoximine analogs as HIF-2α inhibitors. From PCT Int. Appl. (2015), WO 2015095048 A1 20150625.

HIF-2α-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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HIF-2α-IN-1 Suppliers

CHINA 26 United States 5 Global 31

MedChemexpress LLC

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CONIER CHEM AND PHARMA LIMITED

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Birdo (Shanghai) Medical Technology Co., Ltd.

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Taizhou Nanfeng Pharmaceutical Research Institute

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1799948-06-3, HIF-2α-IN-1Related Search:

HIF-2α-IN-1

HIF-2&amp

HIF-2 Alpha -IN-1

Benzonitrile, 3-[[(3R)-4-(difluoromethyl)-2,2-difluoro-2,3-dihydro-3-hydroxy-1,1-dioxidobenzo[b]thien-5-yl]oxy]-5-fluoro-

(R)-3-((4-(difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-dioxido-2,3-dihydrobenzo[b]thiophen-5-yl)oxy)-5-fluorobenzonitrile

3-[[(3R)-4-(difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-dioxo-3H-benzothiophen-5-yl]oxy]-5-fluoro-benzonitrile

HIF 2α IN 1,HIF2αIN1

HIF-2α-IN-1, 10 mM in DMSO

1799948-06-3

C16H8F5NO4S