ChemicalBook > CAS DataBase List > Fumarate hydratase-IN-1
Fumarate hydratase-IN-1
- Product Name
- Fumarate hydratase-IN-1
- CAS No.
- 1644060-37-6
- Chemical Name
- Fumarate hydratase-IN-1
- Synonyms
- Fumarate hydratase-IN-1;Fumarate hydratase inhibitor 1;Fumarate hydratase IN 1,Fumarate hydrataseIN1;ethyl (3S,3~{a}R)-3-[2-(methylamino)-2-oxoethyl]-2-oxo-1-[(4-phenylphenyl)methyl]-3,4,5,6-tetrahydroindole-3~{a}-carboxylate;rel-Ethyl (3S,3aR)-1-([1,1'-biphenyl]-4-ylmethyl)-3-(2-(methylamino)-2-oxoethyl)-2-oxo-1,2,3,4,5,6-hexahydro-3aH-indole-3a-carboxylate;rel-Ethyl (3S,3aR)-1-([1,1'-biphenyl]-4-ylmethyl)-3-(2-(methylamino)-2-oxoethyl)-2-oxo-1,2,3,4,5,6-hexahydro-3aH-indole-3a-carboxylate;3aH-Indole-3a-carboxylic acid, 1-([1,1'-biphenyl]-4-ylmethyl)-1,2,3,4,5,6-hexahydro-3-[2-(methylamino)-2-oxoethyl]-2-oxo-, ethyl ester, (3R,3aS)-rel-
- CBNumber
- CB83126699
- Molecular Formula
- C27H30N2O4
- Formula Weight
- 446.54
- MOL File
- 1644060-37-6.mol
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Fumarate hydratase-IN-1 Property
- Boiling point:
- 693.0±55.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 50 mg/mL (111.97 mM)
- form
- Solid
- pka
- 15.97±0.46(Predicted)
- color
- Off-white to yellow
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-5629
- Product name
- Fumaratehydratase-IN-1
- Purity
- 99.63%
- Packaging
- 5mg
- Price
- $264
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-5629
- Product name
- Fumaratehydratase-IN-1
- Purity
- 99.63%
- Packaging
- 10mg
- Price
- $384
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-5629
- Product name
- Fumaratehydratase-IN-1
- Purity
- 99.63%
- Packaging
- 2mg
- Price
- $168
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-5629
- Product name
- Fumaratehydratase-IN-1
- Purity
- 99.63%
- Packaging
- 50mg
- Price
- $1176
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-5629
- Product name
- Fumaratehydratase-IN-1
- Purity
- 99.63%
- Packaging
- 100mg
- Price
- $1980
- Updated
- 2021/12/16
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Fumarate hydratase-IN-1 Chemical Properties,Usage,Production
Uses
Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM[1].
References
[1] Takeuchi T et al. Identification of Fumarate Hydratase Inhibitors with Nutrient-Dependent Cytotoxicity. J Am Chem Soc, 2015 Jan 21, 137(2): 564-567. DOI:10.1021/ja5101257
Fumarate hydratase-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Fumarate hydratase-IN-1 manufacturers
Shaanxi Dideu New Materials Co. Ltd
- Product
- Fumarate hydratase-IN-1 1644060-37-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-10