ChemicalBook > CAS DataBase List > 3-Hydroxy Agomelatine

3-Hydroxy Agomelatine

Product Name
3-Hydroxy Agomelatine
CAS No.
166526-99-4
Chemical Name
3-Hydroxy Agomelatine
Synonyms
3-Hydroxyagomelatine;Agomelatine Impurity 37;D3-3-Hydroxy Agomelatine;Agomelatine 3-Hydroxy Impurity;N-[2-(7-methoxy-3-hydroxynaphth-1-yl)ethyl]-acetamide;N-(2-(3-Hydroxy-7-methoxynaphthalen-1-yl)ethyl)acetamide;Acetamide, N-[2-(3-hydroxy-7-methoxy-1-naphthalenyl)ethyl]-;Agomelatine impurity 1/3-Hydroxy Agomelatine/N-[2-(3-Hydroxy-7-methoxy-1-naphthalenyl)ethyl]acetamide
CBNumber
CB83133666
Molecular Formula
C15H17NO3
Formula Weight
259.3
MOL File
166526-99-4.mol
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3-Hydroxy Agomelatine Property

Boiling point:
545.8±40.0 °C(Predicted)
Density 
1.190±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
pka
9.85±0.40(Predicted)
form 
Solid
color 
Off-white to light brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
H798280
Product name
3-Hydroxyagomelatine
Packaging
10mg
Price
$1455
Updated
2021/12/16
ChemScene
Product number
CS-0111221
Product name
3-Hydroxyagomelatine
Packaging
5mg
Price
$480
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
95537
Product name
3-Hydroxyagomelatine
Packaging
10mg
Price
$850
Updated
2021/12/16
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3-Hydroxy Agomelatine Chemical Properties,Usage,Production

Uses

3-Hydroxyagomelatine-d3 is an isotope labelled compound of 3-Hydroxyagomelatine, which is an intermediate in the synthesis of 1-(aminoethyl)naphthalene derivative with potential binding affinity for melatonin receptors.

in vivo

Increasing doses (from 1.25 to 40 mg/kg, intraperitoneal injection) of 3-Hydroxy agomelatine (S 21540) does not affect the penile erections induced by mCPP and Ro 60-0175 in Wistar rat[1].

IC 50

5-HT2C Receptor: 3.2 μM (IC50); 5-HT2C Receptor: 1.8 μM (Ki)

3-Hydroxy Agomelatine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Hydroxy Agomelatine Suppliers

China 41 India 4 United States 7 Global 52
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7471
Advantage
65
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18333
Advantage
56
Artis Biotech Co. Ltd.
Tel
028-67271278 18628360895
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
1960
Advantage
58
Roark Standards
Tel
0755-83552066 15986688328
Fax
0755-83552066
Email
service@roarkstandards.com
Country
China
ProdList
1442
Advantage
58
Shanghai Champ Biopharmaceuticals Co., Ltd.
Tel
021-61537865 13585780846
Email
sales@champchem.com
Country
China
ProdList
327
Advantage
58
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-0755-28967200-8062 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9624
Advantage
60
Chengdu Novel Biomedical Co., Ltd.
Tel
028-85255396 18302801538
Fax
028-85255396
Email
cdnovell@163.com
Country
China
ProdList
2389
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
Shenzhen Botel Biotechnology Co. Ltd.
Tel
13316949107 13316968096
Email
1979313431@qq.com
Country
China
ProdList
9564
Advantage
58

166526-99-4, 3-Hydroxy AgomelatineRelated Search:

2-(7-Methoxynaphthalen-1-yl)acetamide 7-DesMethylagoMelatine 2-(7-Hydroxy-1-naphthyl)ethylaMine 2-(7-Methoxynaphthalen-1-yl)acetic acid 7-DesMethyl-3-hydroxyagoMelatine (E)-2-(7-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)ethan-1-amine 1-NaphthaleneacetaMide, 1,2,3,4-tetrahydro-7-Methoxy- 1-Hydroxy-7-Methoxy-1,2,3,4-tetrahydronaphthalene 2-(7-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)ethan-1-amine AgoMelatine-D6 2-(7-methoxy-3,4-dihydronaphthalen-1-yl)ethan-1-amine N-acetyl-N-(2-(7-Methoxynaphthalen-1-yl)ethyl)acetaMide 7-METHOXY-1-NAPHTHOL AGOMELATINE AcetaMide, N,N-bis[2-(7-Methoxy-1-naphthalenyl)ethyl]- 3,4-Dihydro Agomelatine Desacetyl-7-desMethyl AgoMelatine HydrobroMide 2-(7-Methoxy-1-naphthyl)ethylamine hydrochloride

  • Agomelatine 3-Hydroxy Impurity
  • Agomelatine impurity 1/3-Hydroxy Agomelatine/N-[2-(3-Hydroxy-7-methoxy-1-naphthalenyl)ethyl]acetamide
  • N-[2-(7-methoxy-3-hydroxynaphth-1-yl)ethyl]-acetamide
  • N-(2-(3-Hydroxy-7-methoxynaphthalen-1-yl)ethyl)acetamide
  • Acetamide, N-[2-(3-hydroxy-7-methoxy-1-naphthalenyl)ethyl]-
  • Agomelatine Impurity 37
  • 3-Hydroxyagomelatine
  • D3-3-Hydroxy Agomelatine
  • 166526-99-4