BX 430

Product Name: BX 430
CAS No.: 688309-70-8
Chemical Name: BX 430
Synonyms: BX 430;BX430, 10 mM in DMSO;1-(2,6-Dibromo-4-isopropylphenyl)-3-(pyridin-3-yl)urea;N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea;Urea, N-[2,6-dibromo-4-(1-methylethyl)phenyl]-N'-3-pyridinyl-;P2X Receptor,Ca channels,BX430,chronic,channels,species,P2XRs,Inhibitor,disease,Ca2+ channels,BX 430,cardiovascular,P2X4,receptor,specificity,inhibit,Calcium Channel,human,pain,BX-430
CBNumber: CB83146266
Molecular Formula: C15H15Br2N3O
Formula Weight: 413.11
MOL File: 688309-70-8.mol

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BX 430 Property

Melting point:: 164-168°C
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris

Product number: 5545
Product name: BX430
Purity: ≥99%(HPLC)
Packaging: 10
Price: $169
Updated: 2021/12/16

Tocris

Product number: 5545
Product name: BX430
Purity: ≥99%(HPLC)
Packaging: 50
Price: $711
Updated: 2021/12/16

TRC

Product number: B810555
Product name: BX430
Packaging: 10mg
Price: $395
Updated: 2021/12/16

ChemScene

Product number: CS-0033101
Product name: BX430
Purity: 99.87%
Packaging: 50mg
Price: $500
Updated: 2021/12/16

ChemScene

Product number: CS-0033101
Product name: BX430
Purity: 99.87%
Packaging: 5mg
Price: $85
Updated: 2021/12/16

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BX 430 Chemical Properties,Usage,Production

Uses

BX 430 is a selective P2X4 allosteric antagonist in human and zebrafish.

Biological Activity

BX430 is a selective noncompetitive allosteric antagonist of human P2X4 receptor channels. P2X4 receptors are highly expressed in the CNS, and have been studied as a therapeutic target for neuropathic pain and inflammation, and treatment of traumatic brain injury, cerebral ischemia, and spinal cord injury. BX430 is highly selective for human P2X4, with minimal activity towards other P2X subtypes, including P2X1–P2X3, P2X5, and P2X7. BX430 is also an antagonist of zebrafish P2X4 but has no effect on r at and mouse P2X4 receptors. BX430 has an IC50 value of 540 nM.

storage

Store at +4°C

BX 430 Preparation Products And Raw materials

Raw materials

Preparation Products

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BX 430 Suppliers

China 35 India 1 United Kingdom 1 United States 8 Global 45

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 14055
Advantage: 65

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 5944
Advantage: 55

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7312
Advantage: 58

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Shanghai Dongyang Biotechnology Co., Ltd.

Tel: 0512-0512-13601744364 13601744364
Email: chemsharker@126.com
Country: China
ProdList: 929
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

688309-70-8, BX 430Related Search:

BX 430

N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea

Urea, N-[2,6-dibromo-4-(1-methylethyl)phenyl]-N'-3-pyridinyl-

1-(2,6-Dibromo-4-isopropylphenyl)-3-(pyridin-3-yl)urea

P2X Receptor,Ca channels,BX430,chronic,channels,species,P2XRs,Inhibitor,disease,Ca2+ channels,BX 430,cardiovascular,P2X4,receptor,specificity,inhibit,Calcium Channel,human,pain,BX-430

BX430, 10 mM in DMSO

688309-70-8