ChemicalBook > CAS DataBase List > GTQTUABHRCWVLL-UHFFFAOYSA-N

GTQTUABHRCWVLL-UHFFFAOYSA-N

Product Name: GTQTUABHRCWVLL-UHFFFAOYSA-N
CAS No.: 1383450-81-4
Chemical Name: GTQTUABHRCWVLL-UHFFFAOYSA-N
Synonyms: JNJ-678);Rilematovir;Rilematovir (JNJ-678);JNJ-678 (JNJ-53718678);JNJ-53718678 (JNJ53718678;Rilematovir, 10 mM in DMSO;GTQTUABHRCWVLL-UHFFFAOYSA-N;Rilematovir (Synonyms: JNJ-678;GTQTUABHRCWVLL-UHFFFAOYSA-N,JNJ-53718678;3-((5-Chloro-1-(3-(methylsulfonyl)propyl)-1H-indol-2-yl)methyl)-1-(2,2,2-trifluoroethyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one
CBNumber: CB83147021
Molecular Formula: C21H20ClF3N4O3S
Formula Weight: 500.92
MOL File: 1383450-81-4.mol

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GTQTUABHRCWVLL-UHFFFAOYSA-N Property

Boiling point:: 672.5±55.0 °C(Predicted)
Density: 1.50±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:65.0(Max Conc. mg/mL);129.76(Max Conc. mM)
form: A crystalline solid
pka: 6.39±0.20(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0043622
Product name: JNJ-678
Purity: 98.22%
Packaging: 5mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0043622
Product name: JNJ-678
Purity: 98.22%
Packaging: 10mg
Price: $750
Updated: 2021/12/16

ChemScene

Product number: CS-0043622
Product name: JNJ-678
Purity: 98.22%
Packaging: 25mg
Price: $1500
Updated: 2021/12/16

ChemScene

Product number: CS-0043622
Product name: JNJ-678
Purity: 98.22%
Packaging: 50mg
Price: $2100
Updated: 2021/12/16

ChemScene

Product number: CS-0043622
Product name: JNJ-678
Purity: 98.22%
Packaging: 100mg
Price: $3300
Updated: 2021/12/16

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GTQTUABHRCWVLL-UHFFFAOYSA-N Chemical Properties,Usage,Production

Uses

Rilematovir (JNJ-678) is a novel fusion protein inhibitor. Rilematovir has the potential for respiratory syncytial virus (RSV) research.

in vivo

Oral treatment of neonatal lambs with Rilematovir, or with an equally active close analog, efficiently inhibits established acute lower respiratory tract infection in the animals, even when treatment is delayed until external signs of respiratory syncytial virus illness have become visible^[1].

References

[1] Roymans D, et al. Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor. Nat Commun. 2017 Aug 1;8(1):167. DOI:10.1038/s41467-017-00170-x

GTQTUABHRCWVLL-UHFFFAOYSA-N Preparation Products And Raw materials

Raw materials

Preparation Products

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GTQTUABHRCWVLL-UHFFFAOYSA-N Suppliers

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1383450-81-4, GTQTUABHRCWVLL-UHFFFAOYSA-NRelated Search:

GTQTUABHRCWVLL-UHFFFAOYSA-N

JNJ-53718678 (JNJ53718678

JNJ-678)

3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one

2H-Imidazo[4,5-c]pyridin-2-one, 3-[[5-chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl]methyl]-1,3-dihydro-1-(2,2,2-trifluoroethyl)-

JNJ-678 (JNJ-53718678)

GTQTUABHRCWVLL-UHFFFAOYSA-N,JNJ-53718678

Rilematovir (Synonyms: JNJ-678

3-((5-Chloro-1-(3-(methylsulfonyl)propyl)-1H-indol-2-yl)methyl)-1-(2,2,2-trifluoroethyl)-1H-imidazo[4,5-c]pyridin-2(3H)-one

Rilematovir

Rilematovir (JNJ-678)

Rilematovir, 10 mM in DMSO

1383450-81-4

C21H20ClF3N4O3S