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N-Me-L-Ala-maytansinol

Product Name
N-Me-L-Ala-maytansinol
CAS No.
77668-69-0
Chemical Name
N-Me-L-Ala-maytansinol
Synonyms
AP3 Intermidate;AP3 Intermidate 1;N-Me-L-Ala-maytansinol;Maytansine, N2'-deacetyl-;maytansinol 3-(S)-α-N-methylaminopropionate;Benzoicacid,4-fluoro-,(5-bromo-4-methoxyphenyl)methylester;(1S,2R,3S,5S,6R,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.11?,1?.03,?]hexacosa-10,12,14(26),16,18-pentaen-6-yl (2S)-2-(methylamino)propanoate
CBNumber
CB83147258
Molecular Formula
C32H44ClN3O9
Formula Weight
650.17
MOL File
77668-69-0.mol
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N-Me-L-Ala-maytansinol Property

Boiling point:
849.5±65.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
pka
9.82±0.70(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Me-L-Ala-maytansinol Chemical Properties,Usage,Production

Description

Maytansinoid-Ala is a potent microtubule-targeted compound that inhibits proliferation of cells at mitosis. Maytansinoid-Ala can be used for synthesis of ADCs. The microtubule-targeting maytansinoids accumulate in cells and induce mitotic arrest at 250- to 1000-fold lower concentrations than those required for their association with tubulin or microtubules.

N-Me-L-Ala-maytansinol Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Me-L-Ala-maytansinol Suppliers

TargetMol Chemicals Inc.
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View Lastest Price from N-Me-L-Ala-maytansinol manufacturers

Jiangsu Nata Opto-electronic Material Co.,Ltd.
Product
N-Me-L-Ala-maytansinol 77668-69-0
Price
US $0.00/G
Min. Order
5G
Purity
98%
Supply Ability
1KG
Release date
2023-05-24

77668-69-0, N-Me-L-Ala-maytansinolRelated Search:


  • AP3 Intermidate 1
  • maytansinol 3-(S)-α-N-methylaminopropionate
  • AP3 Intermidate
  • N-Me-L-Ala-maytansinol
  • Maytansine, N2'-deacetyl-
  • Benzoicacid,4-fluoro-,(5-bromo-4-methoxyphenyl)methylester
  • (1S,2R,3S,5S,6R,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.11?,1?.03,?]hexacosa-10,12,14(26),16,18-pentaen-6-yl (2S)-2-(methylamino)propanoate
  • 77668-69-0
  • C32H44ClN3O9