Centanafadine HCl

Product Name: Centanafadine HCl
CAS No.: 923981-14-0
Chemical Name: Centanafadine HCl
Synonyms: CTN SR;EB-1020 SR;Centanafadine HCl;EB-1020 hydrochloride;Centafadine hydrochloride;Centanafadine hydrochloride, 10 mM in DMSO;Centanafadine hydrochloride (EB-1020 (hydrochloride));Centanafadine hydrochloride (Synonyms: EB-1020 (hydrochloride));(1R,5S)-(+)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane hydrochloride;Centanafadine,SLC6A3,5-HTT,EB 1020,Centanafadine hydrochloride,Dopamine Transporter,SLC6A4,Beta Receptor,DAT,EB-1020,inhibit,SERT,Serotonin Transporter,EB1020,Adrenergic Receptor,Inhibitor
CBNumber: CB83151653
Molecular Formula: C15H16ClN
Formula Weight: 245.75
MOL File: 923981-14-0.mol

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Centanafadine HCl Property

storage temp.: Store at -20°C
solubility: DMSO: 125 mg/mL (508.65 mM)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H228Flammable solid

H252Self-heating in large quantities; may catch fire

H360May damage fertility or the unborn child

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P235+P410Keep cool. Protect from sunlight.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P391Collect spillage. Hazardous to the aquatic environment

P407Maintain air gap between stacks/pallets.

P413Store bulk masses greater than … kg/…lbs at temperatures not exceeding … oC/…oF.

P420Store away from other materials.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: C256620
Product name: CentanafadineHydrochloride
Packaging: 100mg
Price: $1320
Updated: 2021/12/16

ChemScene

Product number: CS-0077776
Product name: Centanafadinehydrochloride
Purity: 99.93%
Packaging: 5mg
Price: $205
Updated: 2021/12/16

ChemScene

Product number: CS-0077776
Product name: Centanafadinehydrochloride
Purity: 99.93%
Packaging: 10mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0077776
Product name: Centanafadinehydrochloride
Purity: 99.93%
Packaging: 50mg
Price: $1200
Updated: 2021/12/16

ChemScene

Product number: CS-0077776
Product name: Centanafadinehydrochloride
Purity: 99.93%
Packaging: 100mg
Price: $2100
Updated: 2021/12/16

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Centanafadine HCl Chemical Properties,Usage,Production

Uses

Centanafadine Hydrochloride is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) used as a treatment for attention deficit hyperactivity disorder (ADHD) that is in phase II clinical trials.

in vivo

In microdialysis studies, Centanafadine markedly increases NE, and DA concentrations levels in rat prefrontal cortex in vivo with peak increases of 375 and 300%, respectively with the greatest effects on NE, and also increases DA extracellular concentrations in the striatum to 400% of baseline concentrations. Behavioral studies demonstrate that Centanafadine dose-dependently decreases immobility in the mouse tail suspension test of depression to 13% of control levels, and do not stimulate locomotor activity in adult rats in the optimal dose range. Centanafadine dose-dependently inhibits locomotor hyperactivity in juvenile rats lesioned with the neurotoxin 6-hydroxydopamine (100 μg intracisternally) as neonates; a well-established animal model for attention-deficit hyperactivity disorder (ADHD)^[1].

Centanafadine HCl Preparation Products And Raw materials

Raw materials

Preparation Products

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Centanafadine HCl Suppliers

China 25 United States 3 Global 28

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923981-14-0, Centanafadine HClRelated Search:

Centanafadine HCl

Centanafadine hydrochloride (EB-1020 (hydrochloride))

(1R,5S)-(+)-1-(naphthalen-2-yl)-3-azabicyclo[3.1.0]hexane hydrochloride

Centanafadine hydrochloride (Synonyms: EB-1020 (hydrochloride))

Centafadine hydrochloride

EB-1020 hydrochloride

CTN SR

EB-1020 SR

Centanafadine,SLC6A3,5-HTT,EB 1020,Centanafadine hydrochloride,Dopamine Transporter,SLC6A4,Beta Receptor,DAT,EB-1020,inhibit,SERT,Serotonin Transporter,EB1020,Adrenergic Receptor,Inhibitor

Centanafadine hydrochloride, 10 mM in DMSO

923981-14-0

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