ChemicalBook > CAS DataBase List > (R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole

(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole

Product Name
(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole
CAS No.
681490-95-9
Chemical Name
(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole
Synonyms
(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole;(R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl 4-Nitrobenzoate;1H-Imidazole-1-propanol, 2-chloro-β-hydroxy-β-methyl-4-nitro-, 1-(4-nitrobenzoate), (βR)-
CBNumber
CB83154144
Molecular Formula
C14H13ClN4O7
Formula Weight
384.73
MOL File
681490-95-9.mol
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(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Property

Melting point:
122-123 °C(Solv: ethyl acetate (141-78-6); isopropyl ether (108-20-3))
Boiling point:
638.9±65.0 °C(Predicted)
Density 
1.58±0.1 g/cm3(Predicted)
solubility 
Chloroform, DCM
form 
Solid
pka
12.81±0.29(Predicted)
color 
Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C367630
Product name
(R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl4-Nitrobenzoate
Packaging
50mg
Price
$525
Updated
2021/12/16
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(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Chemical Properties,Usage,Production

Uses

(R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl 4-Nitrobenzoate is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.

(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole Suppliers

Canada 1 China 6 India 1 United Kingdom 1 Global 9
Toronto Research Chemicals
Tel
--
Fax
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Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71

681490-95-9, (R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazoleRelated Search:


  • (R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole
  • (R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl 4-Nitrobenzoate
  • 1H-Imidazole-1-propanol, 2-chloro-β-hydroxy-β-methyl-4-nitro-, 1-(4-nitrobenzoate), (βR)-
  • 681490-95-9
  • C14H13ClN4O7