HT-2157
- Product Name
- HT-2157
- CAS No.
- 303149-14-6
- Chemical Name
- HT-2157
- Synonyms
- HT-2157;SNAP 37889;HT-2157 ,S0014;HT-2157(SNAP37889);SNAP-37889 (HT-2157);HT-2157, 10 mM in DMSO;SNAP 37889, CID1471834;1-phenyl-3-[3-(trifluoromethyl)phenyl]iminoindol-2-one;1-Phenyl-3-((3-(trifluoromethyl)phenyl)imino)indolin-2-one;1-PHENYL-3-[[3-(TRIFLUOROMETHYL)PHENYL]IMINO]-1H-INDOL-2-ONE
- CBNumber
- CB83155060
- Molecular Formula
- C21H13F3N2O
- Formula Weight
- 366.34
- MOL File
- 303149-14-6.mol
HT-2157 Property
- Melting point:
- 141-144 °C
- Boiling point:
- 484.0±55.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF:30.0(Max Conc. mg/mL);81.89(Max Conc. mM)
DMSO:44.0(Max Conc. mg/mL);120.11(Max Conc. mM)
Ethanol:7.0(Max Conc. mg/mL);19.11(Max Conc. mM) - form
- A solid
- pka
- -0.36±0.20(Predicted)
- color
- Yellow to orange
N-Bromosuccinimide Price
- Product number
- S610985
- Product name
- SNAP37889
- Packaging
- 10mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- CS-6094
- Product name
- HT-2157
- Purity
- >98.0%
- Packaging
- 1mg
- Price
- $108
- Updated
- 2021/12/16
- Product number
- CS-6094
- Product name
- HT-2157
- Purity
- >98.0%
- Packaging
- 5mg
- Price
- $324
- Updated
- 2021/12/16
- Product number
- API0025692
- Product name
- SNAP 37889
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $502.55
- Updated
- 2021/12/16
- Product number
- CS-6094
- Product name
- HT-2157
- Purity
- >98.0%
- Packaging
- 10mg
- Price
- $516
- Updated
- 2021/12/16
HT-2157 Chemical Properties,Usage,Production
Uses
SNAP 37889 is a galanin-3 receptor antagonist that suppresses alcohol drinking and morphine self-administration.
in vivo
The galanin-3 receptor antagonist, HT-2157 (SNAP 37889), reduces operant responding for ethanol in alcohol-preferring rats. The novel selective GALR3 antagonist, HT-2157, to reduce anxiety-like behaviour and voluntary ethanol consumption in the iP (alcohol-preferring) rat. Male iP rats treated with HT-2157 at a dose of 30 mg/kg (i.p.) do not show altered locomotor activity or changes in anxiety-like behaviour in the elevated plus maze or light-dark paradigms. Treatment with HT-2157 (30 mg/kg, i.p.) reduces operant responding for solutions containing ethanol, sucrose and saccharin. Collectively, results from the current study shows that HT-2157 (30 mg/kg, i.p.) is effective in reducing operant responding for ethanol[2].
HT-2157 Preparation Products And Raw materials
Raw materials
Preparation Products
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