ChemicalBook > CAS DataBase List > Tegoprazan
Tegoprazan
Drug Approval Medical efficacy- Product Name
- Tegoprazan
- CAS No.
- 942195-55-3
- Chemical Name
- Tegoprazan
- Synonyms
- 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-chromen-4-yl]oxy]-N,N,2-trimethyl-3H-benzimidazole-5-carboxamide;1H-Benzimidazole-5-carboxamide, 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy]-N,N,2-trimethyl-;RQ-4;CJ 12420;Tigorasan;Tegoprazan;RQ-00000004;Tegopmsam Al;Tegoprazan API;Tegoprazan (B)
- CBNumber
- CB83159891
- Molecular Formula
- C20H19F2N3O3
- Formula Weight
- 387.38
- MOL File
- 942195-55-3.mol
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Tegoprazan Property
- Boiling point:
- 596.5±50.0 °C(Predicted)
- Density
- 1.371±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble
- form
- A solid
- pka
- 9.73±0.30(Predicted)
- color
- Off-white to light yellow
- InChI
- InChI=1S/C20H19F2N3O3/c1-10-23-14-6-11(20(26)25(2)3)7-17(19(14)24-10)28-15-4-5-27-16-9-12(21)8-13(22)18(15)16/h6-9,15H,4-5H2,1-3H3,(H,23,24)/t15-/m0/s1
- InChIKey
- CLIQCDHNPDMGSL-HNNXBMFYSA-N
- SMILES
- C1(C)NC2=C(O[C@@H]3C4=C(F)C=C(F)C=C4OCC3)C=C(C(N(C)C)=O)C=C2N=1
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N-Bromosuccinimide Price
TRC
- Product number
- T145030
- Product name
- Tegoprazan
- Packaging
- 0.5mg
- Price
- $235
- Updated
- 2021/12/16
TRC
- Product number
- T145030
- Product name
- Tegoprazan
- Packaging
- 5mg
- Price
- $2365
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0014702
- Product name
- Tegoprazan
- Purity
- 98.85%
- Packaging
- 50mg
- Price
- $1450
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0014702
- Product name
- Tegoprazan
- Purity
- 98.85%
- Packaging
- 100mg
- Price
- $2250
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0014702
- Product name
- Tegoprazan
- Purity
- 98.85%
- Packaging
- 5mg
- Price
- $300
- Updated
- 2021/12/16
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Tegoprazan Chemical Properties,Usage,Production
Drug Approval
Tegoprazan was approved by the Ministry of Food and Drug Safety (MFDS) for marketing in July 2018 for the treatment of gastroesophageal reflux disease and erosive esophagitis. Tegoprazan was originally developed by Pfizer. In 2008, it was licensed to RaQualiaPharma (separated from Pfizer) for joint development. In 2014, Tegoprazan was licensed to CJHealthCare by RaQualiaPharma. Finally, CJHealthCare was successfully developed and marketed in Korea. The drug was first marketed in South Korea.
Medical efficacy
Tegoprazan is medicine for treating gastroesophageal reflux disease and erosive esophagitis. Proton pump hydrogen ion/potassium ion exchange ATPase is the main pharmacological target for the treatment of gastric acid-related diseases. Potassium-competitive acid blocker (P-CAB) can inhibit gastric acid secretion by competitively binding to K+ with H+/K+-ATPase. Research finds that Tegoprazan is such a potassium-competitive acid blocker and is considered to be the most advanced drug for treating gastroesophageal reflux disease, because proton pump inhibitors are the most commonly used drugs for treating gastroesophageal reflux disease.
Uses
Tegoprazan is used for remedying and treating nocturnal acid breakthrough symptoms, such as GERD, ulcer, Barrett''s esophagus, and heartburn.
Tegoprazan Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Tegoprazan manufacturers
HangZhou RunYan Pharma Technology Co.,LTD.
- Product
- Tegoprazan 942195-55-3
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000
- Release date
- 2024-09-04
Hebei Zhuanglai Chemical Trading Co.,Ltd
- Product
- Tegoprazan 942195-55-3
- Price
- US $45.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/Week
- Release date
- 2024-05-10
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
- Product
- Tegoprazan 942195-55-3
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- More Than 99%
- Supply Ability
- 100kg/Month
- Release date
- 2024-07-23