ChemicalBook > CAS DataBase List > Cefiderocol
Cefiderocol
- Product Name
- Cefiderocol
- CAS No.
- 1225208-94-5
- Chemical Name
- Cefiderocol
- Synonyms
- Cefiderocol;2H6]-Cefiderocol;2H8]-Cefiderocol;Cefiderocol (S-649266);(6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-(((2-carboxypropan-2-yl)oxy)imino)acetamido)-3-((1-(2-(2-chloro-3,4-dihydroxybenzamido)ethyl)pyrrolidin-1-ium-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- CBNumber
- CB83159907
- Molecular Formula
- C30H34ClN7O10S2
- Formula Weight
- 752.21
- MOL File
- 1225208-94-5.mol
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Cefiderocol Property
- storage temp.
- Store at -20°C, stored under nitrogen,unstable in solution, ready to use.
- solubility
- DMSO:50.0(Max Conc. mg/mL);66.47(Max Conc. mM)
- form
- Solid
- color
- White to off-white
- InChIKey
- DBPPRLRVDVJOCL-OLKYWZQRNA-N
- SMILES
- C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC(C)(C)C(=O)O)C(=O)N12)C[N+]1(CCCC1)CCNC(C1C=CC(O)=C(O)C=1Cl)=O)(=O)[O-] |&1:5,7,r|
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SBR00041
- Product name
- Cefiderocol
- Packaging
- 2 mg
- Price
- $347
- Updated
- 2025/07/31
ChemScene
- Product number
- CS-0016784
- Product name
- Cefiderocol
- Purity
- 98.65%
- Packaging
- 5mg
- Price
- $590
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0016784
- Product name
- Cefiderocol
- Purity
- 98.65%
- Packaging
- 10mg
- Price
- $890
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0016784
- Product name
- Cefiderocol
- Purity
- 98.65%
- Packaging
- 25mg
- Price
- $1900
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0016784
- Product name
- Cefiderocol
- Purity
- 98.65%
- Packaging
- 50mg
- Price
- $3500
- Updated
- 2021/12/16
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Cefiderocol Chemical Properties,Usage,Production
Uses
Cefiderocol, is a novel parenteral siderophore cephalosporin conjugated with a catechol moiety, that has a characteristic antibacterial spectrum with a potent activity against a broad range of aerobic Gram-negative bacterial species,
reaction suitability
reagent type: chelator
Pharmaceutical Applications
Cefiderocol can be used for the treatment of complicated urinary tract infections (cUTIs) when other treatment options are limited or nonexistent.
Biological Activity
Mode of Action: Cefiderocol binds to specific proteins called penicillin-binding proteins (PBPs) located on the bacterial cell wall. This binding affinity inhibits the synthesis of the bacterial cell wall, leading to cell lysis and bacterial death.
Antimicrobial Spectrum: Cefiderocol has strong antimicrobial properties, especially against a wide spectrum of Gram-negative pathogens. Due to its siderophore core it is also a natural iron-chelator, which adds to its antibacterial activities.
Synthesis
Below shows the synthesis route of Cefiderocol
IC 50
β-lactam
Cefiderocol Preparation Products And Raw materials
Raw materials
Preparation Products
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