ChemicalBook > CAS DataBase List > Thiomyristoyl

Thiomyristoyl

Product Name
Thiomyristoyl
CAS No.
1429749-41-6
Chemical Name
Thiomyristoyl
Synonyms
Thiomyristoyl;Thiomyristoyl, 10 mM in DMSO;Thiomyristoyl,Inhibitor,Sirtuin,inhibit;Carbamic acid, N-[(1S)-1-[(phenylamino)carbonyl]-5-[(1-thioxotetradecyl)amino]pentyl]-, phenylmethyl ester;N-?[(1S)?-?1-?[(Phenylamino)?carbonyl]?-?5-?[(1-?thioxotetradecyl)?amino]?pentyl]?-carbamic Acid Phenylmethyl Ester
CBNumber
CB83160422
Molecular Formula
C34H51N3O3S
Formula Weight
581.85
MOL File
1429749-41-6.mol
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Thiomyristoyl Property

Density 
1.077±0.06 g/cm3(Predicted)
storage temp. 
Room temperature
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 2 mg/ml
form 
A crystalline solid
pka
11.20±0.46(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19398
Product name
Thiomyristoyl
Purity
≥98%
Packaging
1mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
19398
Product name
Thiomyristoyl
Purity
≥98%
Packaging
5mg
Price
$302
Updated
2024/03/01
Cayman Chemical
Product number
19398
Product name
Thiomyristoyl
Purity
≥98%
Packaging
10mg
Price
$481
Updated
2024/03/01
Cayman Chemical
Product number
19398
Product name
Thiomyristoyl
Purity
≥98%
Packaging
25mg
Price
$1051
Updated
2024/03/01
TRC
Product number
T344750
Product name
N-​[(1S)​-​1-​[(Phenylamino)​carbonyl]​-​5-​[(1-​thioxotetradecyl)​amino]​pentyl]​-carbamicAcidPhenylmethylEster
Packaging
10mg
Price
$420
Updated
2021/12/16
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Thiomyristoyl Chemical Properties,Usage,Production

Uses

N-?[(1S)?-?1-?[(Phenylamino)?carbonyl]?-?5-?[(1-?thioxotetradecyl)?amino]?pentyl]?-carbamic Acid Phenylmethyl Ester is a potent and specific SIRT2 inhibitor. It exhibits a broad anticancer effect in various human cancer cells and mouse models of breast cancer.

in vivo

TM inhibits tumor growth in mouse models of breast cancer. TM does not cause significant toxicity in mice and no significant weight loss is observed in TM-treated mice. S5H, the acetyl-a-tubulin level is moderately but statistically significantly increased in tumors from TM-treated mice compared with those from vehicle-treated mice, suggesting that TM indeed inhibits SIRT2in vivo[1].

IC 50

SIRT2: 28 nM (IC50); SIRT1: 98 μM (IC50)

Thiomyristoyl Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Thiomyristoyl manufacturers

Career Henan Chemical Co
Product
Thiomyristoyl 1429749-41-6
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23

1429749-41-6, ThiomyristoylRelated Search:


  • Thiomyristoyl
  • Carbamic acid, N-[(1S)-1-[(phenylamino)carbonyl]-5-[(1-thioxotetradecyl)amino]pentyl]-, phenylmethyl ester
  • N-?[(1S)?-?1-?[(Phenylamino)?carbonyl]?-?5-?[(1-?thioxotetradecyl)?amino]?pentyl]?-carbamic Acid Phenylmethyl Ester
  • Thiomyristoyl,Inhibitor,Sirtuin,inhibit
  • Thiomyristoyl, 10 mM in DMSO
  • 1429749-41-6
  • C34H51N3O3S