Thiomyristoyl
- Product Name
- Thiomyristoyl
- CAS No.
- 1429749-41-6
- Chemical Name
- Thiomyristoyl
- Synonyms
- Thiomyristoyl;Thiomyristoyl, 10 mM in DMSO;Thiomyristoyl,Inhibitor,Sirtuin,inhibit;Carbamic acid, N-[(1S)-1-[(phenylamino)carbonyl]-5-[(1-thioxotetradecyl)amino]pentyl]-, phenylmethyl ester;N-?[(1S)?-?1-?[(Phenylamino)?carbonyl]?-?5-?[(1-?thioxotetradecyl)?amino]?pentyl]?-carbamic Acid Phenylmethyl Ester
- CBNumber
- CB83160422
- Molecular Formula
- C34H51N3O3S
- Formula Weight
- 581.85
- MOL File
- 1429749-41-6.mol
Thiomyristoyl Property
- Density
- 1.077±0.06 g/cm3(Predicted)
- storage temp.
- Room temperature
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 2 mg/ml
- form
- A crystalline solid
- pka
- 11.20±0.46(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 19398
- Product name
- Thiomyristoyl
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 19398
- Product name
- Thiomyristoyl
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $302
- Updated
- 2024/03/01
- Product number
- 19398
- Product name
- Thiomyristoyl
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $481
- Updated
- 2024/03/01
- Product number
- 19398
- Product name
- Thiomyristoyl
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $1051
- Updated
- 2024/03/01
- Product number
- T344750
- Product name
- N-[(1S)-1-[(Phenylamino)carbonyl]-5-[(1-thioxotetradecyl)amino]pentyl]-carbamicAcidPhenylmethylEster
- Packaging
- 10mg
- Price
- $420
- Updated
- 2021/12/16
Thiomyristoyl Chemical Properties,Usage,Production
Uses
N-?[(1S)?-?1-?[(Phenylamino)?carbonyl]?-?5-?[(1-?thioxotetradecyl)?amino]?pentyl]?-carbamic Acid Phenylmethyl Ester is a potent and specific SIRT2 inhibitor. It exhibits a broad anticancer effect in various human cancer cells and mouse models of breast cancer.
in vivo
TM inhibits tumor growth in mouse models of breast cancer. TM does not cause significant toxicity in mice and no significant weight loss is observed in TM-treated mice. S5H, the acetyl-a-tubulin level is moderately but statistically significantly increased in tumors from TM-treated mice compared with those from vehicle-treated mice, suggesting that TM indeed inhibits SIRT2in vivo[1].
IC 50
SIRT2: 28 nM (IC50); SIRT1: 98 μM (IC50)
Thiomyristoyl Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Thiomyristoyl manufacturers
- Product
- Thiomyristoyl 1429749-41-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2019-12-23