N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5

Product Name: N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5
CAS No.: 2107273-76-5
Chemical Name: N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5
Synonyms: N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5
CBNumber: CB83163049
Molecular Formula: C63H79ClN4O10
Formula Weight: 1087.79
MOL File: 2107273-76-5.mol

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N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 Property

solubility: Soluble in DMSO, DMF, DCM

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23019
Product name: N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5
Purity: 98%
Packaging: 1mg
Price: $240
Updated: 2021/12/16

BroadPharm

Product number: BP-23019
Product name: N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5
Purity: 98%
Packaging: 2mg
Price: $380
Updated: 2021/12/16

BroadPharm

Product number: BP-23019
Product name: N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5
Purity: 98%
Packaging: 5mg
Price: $680
Updated: 2021/12/16

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N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 Chemical Properties,Usage,Production

Description

N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a Cy5 labeled fluorescent PEG linker containinig DBCO group, which reacts with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalyst. DBCO-activated fluorescein dye will be an ideal alternative to copper intolerant applications. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 Suppliers

China 15 United States 2 Global 17

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N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5

2107273-76-5