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MLi-2

Product Name
MLi-2
CAS No.
1627091-47-7
Chemical Name
MLi-2
Synonyms
MLi-2;MLi2,MLi-2,Inhibitor,Leucine-rich repeat kinase 2,inhibit,disease,orally,LRRK2,Parkinson’s,MLi 2;rel-(2S,6R)-2,6-Dimethyl-4-(6-(5-(1-methylcyclopropoxy)-1H-indazol-3-yl)pyrimidin-4-yl)morpholine;rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole;1H-Indazole, 3-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-pyrimidinyl]-5-[(1-methylcyclopropyl)oxy]-, rel-
CBNumber
CB83167643
Molecular Formula
C21H25N5O2
Formula Weight
379.46
MOL File
1627091-47-7.mol
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MLi-2 Property

Boiling point:
625.8±55.0 °C(Predicted)
Density 
1.257±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 15 mg/ml
form 
A crystalline solid
pka
11.24±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
5756
Product name
MLi-2
Purity
≥98%(HPLC)
Packaging
10
Price
$293
Updated
2021/12/16
Tocris
Product number
5756
Product name
MLi-2
Purity
≥98%(HPLC)
Packaging
50
Price
$1230
Updated
2021/12/16
TRC
Product number
M425473
Product name
MLi-2
Packaging
0.5mg
Price
$235
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD157083
Product name
MLi-2
Packaging
10mg
Price
$175
Updated
2021/12/16
AK Scientific
Product number
1437DY
Product name
cis-2,6-Dimethyl-4-(6-(5-(1-methylcyclopropoxy)-1H-indazol-3-yl)pyrimidin-4-yl)morpholine
Packaging
10mg
Price
$320
Updated
2021/12/16
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MLi-2 Chemical Properties,Usage,Production

Uses

MLi-2 is a leucine-rich repeat kinase 2 (LRRK2) inhibitor and may be used in the treatment and prevention of Parkinson’s disease as its a precursor to the illness.

Definition

ChEBI: MLI-2 is a member of the class of indazoles that is 1H-indazole that is substituted at position 3 by a 6-(cis-2,6-dimethylmorpholin-4-yl)pyrimidin-4-yl group and at position 5 by a (1-methylcyclopropoxy)group. It is an inhibitor of leucine-rich repeat kinase 2 (LRRK2). It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a member of indazoles, a member of pyrimidines, a member of morpholines, a member of cyclopropanes, an aromatic ether and a tertiary amino compound.

storage

Store at -20°C

MLi-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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MLi-2 Suppliers

R&D Scientific Inc.
Tel
+12266000236
Email
sales@rdscientific.com
Country
Canada
ProdList
1307
Advantage
58

1627091-47-7, MLi-2Related Search:


  • MLi-2
  • rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole
  • 1H-Indazole, 3-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-pyrimidinyl]-5-[(1-methylcyclopropyl)oxy]-, rel-
  • rel-(2S,6R)-2,6-Dimethyl-4-(6-(5-(1-methylcyclopropoxy)-1H-indazol-3-yl)pyrimidin-4-yl)morpholine
  • MLi2,MLi-2,Inhibitor,Leucine-rich repeat kinase 2,inhibit,disease,orally,LRRK2,Parkinson’s,MLi 2
  • 1627091-47-7