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CeMMEC1

Product Name
CeMMEC1
CAS No.
440662-09-9
Chemical Name
CeMMEC1
Synonyms
cemmecl;CeMMEC1;CeMMEC1(free base);Epigenetic Reader Domain,CeMMEC-1,Inhibitor,DNA/RNA Synthesis,CeMMEC1,inhibit,CeMMEC 1;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide;4-Isoquinolinecarboxamide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo-;N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
CBNumber
CB83171705
Molecular Formula
C19H16N2O4
Formula Weight
336.34
MOL File
440662-09-9.mol
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CeMMEC1 Property

Boiling point:
590.1±50.0 °C(Predicted)
Density 
1.386±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form 
A crystalline solid
pka
11.38±0.20(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19956
Product name
CeMMEC1
Purity
≥98%
Packaging
500μg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
19956
Product name
CeMMEC1
Purity
≥98%
Packaging
1mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
19956
Product name
CeMMEC1
Purity
≥98%
Packaging
5mg
Price
$243
Updated
2024/03/01
Cayman Chemical
Product number
19956
Product name
CeMMEC1
Purity
≥98%
Packaging
10mg
Price
$426
Updated
2024/03/01
TRC
Product number
C256565
Product name
CeMMEC1
Packaging
5mg
Price
$310
Updated
2021/12/16
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CeMMEC1 Chemical Properties,Usage,Production

Description

CeMMEC1 is an N-methylisoquinolinone that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. This compound synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.

Uses

CeMMEC1, shows high affinity for TAF1, and is an inhibitor of BRD4.

storage

Store at -20°C

CeMMEC1 Preparation Products And Raw materials

Raw materials

Preparation Products

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CeMMEC1 Suppliers

China 43 United States 8 Global 51
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4512
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2992
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7267
Advantage
58
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
9204
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
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View Lastest Price from CeMMEC1 manufacturers

Career Henan Chemical Co
Product
CeMMEC1 440662-09-9
Price
US $0.01/KG
Min. Order
1KG
Purity
98%; 99%
Supply Ability
500g;1kg； 25kg
Release date
2020-01-09

440662-09-9, CeMMEC1Related Search:


  • CeMMEC1
  • cemmecl
  • CeMMEC1(free base)
  • 4-Isoquinolinecarboxamide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo-
  • Epigenetic Reader Domain,CeMMEC-1,Inhibitor,DNA/RNA Synthesis,CeMMEC1,inhibit,CeMMEC 1
  • N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
  • N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
  • 440662-09-9