ChemicalBook > CAS DataBase List > CeMMEC1

CeMMEC1

Product Name
CeMMEC1
CAS No.
440662-09-9
Chemical Name
CeMMEC1
Synonyms
cemmecl;CeMMEC1;CeMMEC1(free base);Epigenetic Reader Domain,CeMMEC-1,Inhibitor,DNA/RNA Synthesis,CeMMEC1,inhibit,CeMMEC 1;N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide;4-Isoquinolinecarboxamide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo-;N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
CBNumber
CB83171705
Molecular Formula
C19H16N2O4
Formula Weight
336.34
MOL File
440662-09-9.mol
More
Less

CeMMEC1 Property

Boiling point:
590.1±50.0 °C(Predicted)
Density 
1.386±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form 
A crystalline solid
pka
11.38±0.20(Predicted)
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
19956
Product name
CeMMEC1
Purity
≥98%
Packaging
500μg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
19956
Product name
CeMMEC1
Purity
≥98%
Packaging
1mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
19956
Product name
CeMMEC1
Purity
≥98%
Packaging
5mg
Price
$243
Updated
2024/03/01
Cayman Chemical
Product number
19956
Product name
CeMMEC1
Purity
≥98%
Packaging
10mg
Price
$426
Updated
2024/03/01
TRC
Product number
C256565
Product name
CeMMEC1
Packaging
5mg
Price
$310
Updated
2021/12/16
More
Less

CeMMEC1 Chemical Properties,Usage,Production

Description

CeMMEC1 is an N-methylisoquinolinone that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. This compound synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.

Uses

CeMMEC1, shows high affinity for TAF1, and is an inhibitor of BRD4.

storage

Store at -20°C

CeMMEC1 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

CeMMEC1 Suppliers

China 43 United States 8 Global 51
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4512
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2990
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7268
Advantage
58
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
10285
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
More
Less

View Lastest Price from CeMMEC1 manufacturers

Career Henan Chemical Co
Product
CeMMEC1 440662-09-9
Price
US $0.01/KG
Min. Order
1KG
Purity
98%; 99%
Supply Ability
500g;1kg； 25kg
Release date
2020-01-09

440662-09-9, CeMMEC1Related Search:


  • CeMMEC1
  • cemmecl
  • CeMMEC1(free base)
  • 4-Isoquinolinecarboxamide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-2-methyl-1-oxo-
  • Epigenetic Reader Domain,CeMMEC-1,Inhibitor,DNA/RNA Synthesis,CeMMEC1,inhibit,CeMMEC 1
  • N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
  • N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
  • 440662-09-9