Nexopamil (racemate)

Product Name: Nexopamil (racemate)
CAS No.: 116759-35-4
Chemical Name: Nexopamil (racemate)
Synonyms: Nexopamil (racemate);5-[N-methyl-N-(n-hexyl)]-amino-2-(3,4,5-trimethoxyphenyl)-2-isopropylvaleronitrile;Benzeneacetonitrile, α-[3-(hexylmethylamino)propyl]-3,4,5-trimethoxy-α-(1-methylethyl)-
CBNumber: CB83175561
Molecular Formula: C24H40N2O3
Formula Weight: 404.6
MOL File: 116759-35-4.mol

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Nexopamil (racemate) Property

Boiling point:: 514.7±50.0 °C(Predicted)
Density: 0.985±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 9?+-.0.50(Predicted)

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Hazard and Precautionary Statements (GHS)

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Nexopamil (racemate) Chemical Properties,Usage,Production

Uses

Nexopamil racemate is the racemate of Nexopamil. Nexopamil is a combined Ca2+/5-HT2 antagonist on thrombus formation in vivo and on platelet aggregation in vitro.

in vivo

Nexopamil (0.05 mg/kg) completely abolishes cyclic flow reductions (CFRs) during the first 30 min after application without significantly altering hemodynamics^[1].

IC 50

5-HT₂ Receptor

References

[1] Kirchengast M, et al. Inhibition by the combined Ca2+ and 5-HT2 receptor antagonist nexopamil (LU 49938) of intracoronary thrombus formation in a canine model of arterial stenosis and intimal damage. J Cardiovasc Pharmacol. 1993 Nov;22(5):687-94. DOI:10.1097/00005344-199311000-00003

Nexopamil (racemate) Preparation Products And Raw materials

Raw materials

Preparation Products

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Nexopamil (racemate) Suppliers

China 8 United States 4 Global 12

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116759-35-4, Nexopamil (racemate)Related Search:

Nexopamil (racemate)

5-[N-methyl-N-(n-hexyl)]-amino-2-(3,4,5-trimethoxyphenyl)-2-isopropylvaleronitrile

Benzeneacetonitrile, α-[3-(hexylmethylamino)propyl]-3,4,5-trimethoxy-α-(1-methylethyl)-

116759-35-4