YUKA1

Product Name: YUKA1
CAS No.: 708991-09-7
Chemical Name: YUKA1
Synonyms: YUKA1;YUKA1,YUKA-1;3H-1,2,4-Triazole-3-thione, 2,4-dihydro-4-[[[3-methoxy-2-(2-propen-1-yloxy)phenyl]methyl]amino]-
CBNumber: CB83175798
Molecular Formula: C13H16N4O2S
Formula Weight: 292.36
MOL File: 708991-09-7.mol

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YUKA1 Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Axon Medchem

Product number: Axon2674
Product name: YUKA1
Purity: 99%
Packaging: 25mg
Price: $478.5
Updated: 2021/12/16

ChemScene

Product number: CS-0020252
Product name: YUKA1
Packaging: 5mg
Price: $1750
Updated: 2021/12/16

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YUKA1 Chemical Properties,Usage,Production

Description

YUKA1 is a cell permeable, potent inhibitor of KDM5A, showing little to no activity against KDM5B, KDM6A, and KDM6B. YUKA1 was shown to increase H3K4me3 levels in human cells and selectively inhibit the proliferation of cancer cells whose growth depends on KDM5A.

Uses

YUKA1 is a potent and cell permeable Lysine demethylase 5A (KDM5A) inhibitor, with an IC50 of 2.66 μM, less active on KDM5C (IC50, 7.12 μM), and is inactive on KDM5B, KDM6A or KDM6B. YUKA1 increases H3K4me3 levels in human cells with anti-cancer activity[1].

IC 50

KDM5

References

[1] Gale M, et al. Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance. Oncotarget. 2016 Jun 28;7(26):39931-39944. DOI:10.18632/oncotarget.9539

YUKA1 Preparation Products And Raw materials

Raw materials

Preparation Products

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YUKA1 Suppliers

China 8 United States 3 Global 11

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32436
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
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TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29342
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Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
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Adooq Bioscience LLC

Tel: 400-025-6535
Email: sales@adooq.cn
Country: China
ProdList: 6215
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Shanghai Amole Biotechnology Co., Ltd.

Tel: 18916360931 18916360931
Email: 2596183085@qq.com
Country: China
ProdList: 17236
Advantage: 58

TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 19961
Advantage: 58

708991-09-7, YUKA1Related Search:

YUKA1

3H-1,2,4-Triazole-3-thione, 2,4-dihydro-4-[[[3-methoxy-2-(2-propen-1-yloxy)phenyl]methyl]amino]-

YUKA1,YUKA-1

708991-09-7