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HOTU

Product Name
HOTU
CAS No.
333717-40-1
Chemical Name
HOTU
Synonyms
HOTU;O-[(Ethoxycarbonyl)cyanomethylenamno]-N,N,N',N'-tetramethyluronium;(1-cyano-2-ethoxy-2-oxoethylidene)amino]oxy-(dimethylamino)methylidene]-dimethylazanium;O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium hexafluorophosphate;6-Cyano-N,N,2-trimethyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-aminium hexafluorophosphate;O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium hexafluorophosphate;HOTUO-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium hexafluorophosphate;HOTU O-[(Ethoxycarbonyl)cyanoMethylenaMino]-N,N,N',N'-tetraMethyluroniuM hexafluorophosphate;O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium hexafluorophosphate(HOTU);6-Cyano-N,N,2-trimethyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-aminium hexafluorophosphate(HOTU)
CBNumber
CB8319953
Molecular Formula
C10H17F6N4O3P
Formula Weight
386.23
MOL File
Mol file
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HOTU Property

Melting point:
128-131 °C
storage temp. 
2-8°C
form 
powder to crystal
color 
White to Almost white
Major Application
peptide synthesis
InChI
InChI=1S/C10H17N4O3.F6P/c1-6-16-9(15)8(7-11)12-17-10(13(2)3)14(4)5;1-7(2,3,4,5)6/h6H2,1-5H3;/q+1;-1/b12-8-;
InChIKey
RKTBAMPZUATMIO-JCTPKUEWSA-N
SMILES
C(=[N+](/C)\C)(\N(C)C)/O/N=C(/C#N)\C(=O)OCC.[P-](F)(F)(F)(F)(F)F
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
F 
8-10-21
HS Code 
2928.00.5000
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
02576
Product name
O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N′,N′-tetramethyluronium hexafluorophosphate
Purity
≥97.0% (HPCE)
Packaging
25g
Price
$379
Updated
2023/06/20
TCI Chemical
Product number
E1306
Product name
O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium Hexafluorophosphate
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$29
Updated
2025/07/31
TCI Chemical
Product number
E1306
Product name
O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium Hexafluorophosphate
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$82
Updated
2025/07/31
TRC
Product number
H669588
Product name
HOTU;O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N'',N''-tetramethyluroniumHexafluorophosphate
Packaging
100mg
Price
$75
Updated
2021/12/16
Activate Scientific
Product number
AS112892
Product name
HOTU
Purity
98%
Packaging
5G
Price
$29
Updated
2021/12/16
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HOTU Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Reagent for peptide coupling

Derivatization for use in peptide synthesis

reaction suitability

reaction type: Coupling Reactions

HOTU Preparation Products And Raw materials

Raw materials

Preparation Products

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HOTU Suppliers

Americas 1 China 87 Europe 1 India 3 Israel 1 Japan 1 Switzerland 1 United Kingdom 2 United States 10 Global 107
Suzhou Highfine Biotech Co., Ltd
Tel
68311833 13962195826
Fax
0512-68417696
Email
wuhao@highfine.com
Country
China
ProdList
475
Advantage
75
Shanghai Medpep Co., Ltd
Tel
021-65566949 13901795941
Fax
86-21-51861665
Email
market@medpep.com
Country
China
ProdList
156
Advantage
66
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3295
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7247
Advantage
62
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3199
Advantage
55
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
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View Lastest Price from HOTU manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
HOTU 333717-40-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-26
Zhuozhou Wenxi import and Export Co., Ltd
Product
HOTU 333717-40-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
HOTU 333717-40-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

333717-40-1, HOTURelated Search:


  • HOTU
  • O-[(Ethoxycarbonyl)cyanomethylenamno]-N,N,N',N'-tetramethyluronium
  • 6-Cyano-N,N,2-trimethyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-aminium hexafluorophosphate
  • O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium hexafluorophosphate(HOTU)
  • HOTU O-[(Ethoxycarbonyl)cyanoMethylenaMino]-N,N,N',N'-tetraMethyluroniuM hexafluorophosphate
  • (1-cyano-2-ethoxy-2-oxoethylidene)amino]oxy-(dimethylamino)methylidene]-dimethylazanium
  • N-(6-Cyano-2-methyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-ylidene)-N-methylmethanaminium hexafluorophosphate(V)
  • O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium hexafluorophosphate
  • HOTUO-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium hexafluorophosphate
  • [[(1-cyano-2-ethoxy-2-oxoethylidene)amino]oxy-(dimethylamino)methylidene]-dimethylazanium,hexafluorophosphate
  • <i>O</i>-[(Ethoxycarbonyl)cyanomethylenamino]-<i>N</i>,<i>N</i>,<i>N</i>′,<i>N</i>′-tetramethyluronium hexafluorophosphate
  • O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N′,N′-tetramethyluronium hexafluorophosphate, CAS 333717-40-1
  • O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium hexafluorophosphate
  • 6-Cyano-N,N,2-trimethyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-aminium hexafluorophosphate(HOTU)
  • 333717-40-1
  • C10H17N4O3PF6
  • C10H17F6N4O3P