Uridine, 5'-azido-5'-deoxy-2'-O-methyl-

Product Name: Uridine, 5'-azido-5'-deoxy-2'-O-methyl-
CAS No.: 194034-68-9
Chemical Name: Uridine, 5'-azido-5'-deoxy-2'-O-methyl-
Synonyms: 5’-Azido-5’-deoxy-2’-O-methyluridine;5'-Azido-5'-deoxy-2'-O-methyluridine;Uridine, 5'-azido-5'-deoxy-2'-O-methyl-;1-[(2R,3R,4R,5R)-5-(azidomethyl)-4-hydroxy-3-methoxy-tetrahydrofuran-2-yl]pyrimidine-2,4-dione
CBNumber: CB83203969
Molecular Formula: C10H13N5O5
Formula Weight: 283.24
MOL File: 194034-68-9.mol

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Uridine, 5'-azido-5'-deoxy-2'-O-methyl- Chemical Properties,Usage,Production

Uses

5’-Azido-5’-deoxy-2’-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 5’-Azido-5’-deoxy-2’-O-methyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

Uridine, 5'-azido-5'-deoxy-2'-O-methyl- Preparation Products And Raw materials

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Uridine, 5'-azido-5'-deoxy-2'-O-methyl- Suppliers

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194034-68-9, Uridine, 5'-azido-5'-deoxy-2'-O-methyl-Related Search:

Uridine, 2',5'-dideoxy-5'-iodo- Uridine, 2',3'-didehydro-2',3'-dideoxy-, 5'-acetate Uridine, 4',5'-didehydro-5'-deoxy- Uridine, 5-cyano- Uridine,4-thio-, 2',3',5'-tribenzoate (6CI,7CI,8CI,9CI) Uridine, 4',5'-didehydro-2',5'-dideoxy- Uridine,3'-azido-2',3'-dideoxy-5-hydroxy-

Uridine, 5'-azido-5'-deoxy-2'-O-methyl-

5'-Azido-5'-deoxy-2'-O-methyluridine

5’-Azido-5’-deoxy-2’-O-methyluridine

1-[(2R,3R,4R,5R)-5-(azidomethyl)-4-hydroxy-3-methoxy-tetrahydrofuran-2-yl]pyrimidine-2,4-dione

194034-68-9