1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione

Product Name: 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione
CAS No.: 69321-95-5
Chemical Name: 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione
Synonyms: Cytarabine 19;Cytarabine Impurity 28;Cytarabine Impurity 17;5-Hydroxy-arabinouridine;2,4(1H,3H)-Pyrimidinedione, 1-β-D-arabinofuranosyl-5-hydroxy-;1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione;1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxypyrimidine-2,4(1H,3H)-dione
CBNumber: CB83265305
Molecular Formula: C9H12N2O7
Formula Weight: 260.20078
MOL File: 69321-95-5.mol

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1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione Property

Density: 1.848±0.06 g/cm3(Predicted)
pka: 8+-.0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione Chemical Properties,Usage,Production

Uses

5-Hydroxy-arabinouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione Suppliers

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69321-95-5, 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dioneRelated Search:

1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxy-pyrimidine-2,4-dione

5-Hydroxy-arabinouridine

Cytarabine Impurity 17

1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-hydroxypyrimidine-2,4(1H,3H)-dione

Cytarabine Impurity 28

2,4(1H,3H)-Pyrimidinedione, 1-β-D-arabinofuranosyl-5-hydroxy-

Cytarabine 19

69321-95-5