2,4(1H,3H)-Pyrimidinedione, 1,6-dimethyl-

2,4(1H,3H)-Pyrimidinedione, 1,6-dimethyl- Property

Melting point:

258-262 °C(Solv: water (7732-18-5); ethanol (64-17-5))

Density 

1.189±0.06 g/cm3(Predicted)

storage temp. 

Store at room temperature

pka

9.80±0.40(Predicted)

Appearance

White to off-white Solid

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

2,4(1H,3H)-Pyrimidinedione, 1,6-dimethyl- Chemical Properties,Usage,Production

Uses

1,6-Dimethyl-1H-pyrimidine-2,4-dione is used as a reagent in the preparation of thio uracil derivatives as intermediates for drugs and agrochemicals. It also acts as a reagent in the preparation of N-(pyridinylmethyl)dimethyl(oxo)pyrrolo[3,2-d]pyrimidinyl)benzenesulfonamide derivatives as A2B adenosine receptor antagonists.