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ROSE BENGAL LACTONE

Product Name
ROSE BENGAL LACTONE
CAS No.
4159-77-7
Chemical Name
ROSE BENGAL LACTONE
Synonyms
Solvent Red 141;ROSE BENGAL LACTONE;4’,5’,7’-tetraiodo-droxy-2;C.I.Solvent Red 141:C.I.45440:1;4,5,6,7-Tetrachloro-2’,4’,5’,7’-tetraiodofluorescein;spiro[isobenzofuran-1(3h),9’-[9h]xanthen]-3-one,4,5,6,7-tetrachloro-3’,6’-dihy;4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[2-benzofuran-3,9'-xanthene]-1-one;4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;4',5',6',7'-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one;3,6-Dihydroxy-2,4,5,7-tetraiodo-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
CBNumber
CB8331887
Molecular Formula
C20H4Cl4I4O5
Formula Weight
973.67
MOL File
4159-77-7.mol
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ROSE BENGAL LACTONE Property

Melting point:
280 °C (dec.)(lit.)
storage temp. 
room temp
Boiling point:
741.8±60.0 °C(Predicted)
Density 
2.96±0.1 g/cm3(Predicted)
pka
7.03±0.20(Predicted)
form 
powder
color 
pink to red
λmax
557 nm
ε(extinction coefficient)
≥10000 at 317-323nm
≥30000 at 516-522nm
≥95000 at 554-560nm
EPA Substance Registry System
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- (4159-77-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
328960
Product name
Rose Bengal lactone
Purity
95%
Packaging
1g
Price
$116
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
DYE0000553
Product name
ROSE BENGAL LACTONE
Purity
95.00%
Packaging
1G
Price
$626.43
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
DYE0000553
Product name
ROSE BENGAL LACTONE
Purity
95.00%
Packaging
5G
Price
$1163.45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
DYE0000553
Product name
ROSE BENGAL LACTONE
Purity
95.00%
Packaging
10G
Price
$1765.08
Updated
2021/12/16
Chem-Impex
Product number
42054
Product name
RoseBengallactone,≥94%(HPLC),suitableforHematology&Histology
Purity
≥94%(HPLC)
Packaging
1G
Price
$95.51
Updated
2021/12/16
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ROSE BENGAL LACTONE Chemical Properties,Usage,Production

Description

Rose bengal lactone is a potent inhibitor of human metabolism that binds to the proteasome pathway and inhibits the polymerization of tubulin. It has been shown to bind with high affinity to microtubules and inhibit their assembly, which leads to cell death. Rose bengal lactone also binds with high affinity to potassium ion, which may contribute to its anti-cancer effects. This compound has also been found to be an effective inhibitor of goiters in rats by binding with aliphatic hydrocarbons such as cholesterol.

Chemical Properties

Bluish-pink powder. Soluble in water.

Uses

Biological stain; colorant for inks, cellulosics, foods, cosmetics, medicine (diagnostic aid).

Preparation

will Resorcinol and 4,5,6,7-Tetrachloroisobenzofuran-1,3-dione condensation, The resulting 4,5,6,7 – tetrachloro-fluorescein tetraiodide.

Properties and Applications

blue light red. Soluble in water for blue light yellow, no fluorescence, in concentrated sulfuric acid for brown, dilution after hot pink precipitation. Used in cosmetics coloring.

Standard Light Fastness Heat-resistant(℃) water Sodium Carbonate(5%) Hydrochloric acid(5%)
Melting point Stable
ISO Poor Insoluble

ROSE BENGAL LACTONE Preparation Products And Raw materials

Raw materials

Preparation Products

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ROSE BENGAL LACTONE Suppliers

Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20)
Fax
0539-6362799(To 20)
Country
China
ProdList
10007
Advantage
58
Henan Alpha Chemical Co., Ltd.
Tel
0371-0371-55055611 18137792234
Fax
QQ:3002694073
Email
3002694073@qq.com
Country
China
ProdList
10279
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49374
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
13774214275
Email
zhouzz@univ-bio.com
Country
China
ProdList
24998
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
SY06@accelachem.com
Country
China
ProdList
8243
Advantage
58
Chengdu Peter-like Biotechnology Co., Ltd.
Tel
028-81700200 13308200041
Email
2851167782@qq.com
Country
China
ProdList
11183
Advantage
58

4159-77-7, ROSE BENGAL LACTONERelated Search:


  • 4’,5’,7’-tetraiodo-droxy-2
  • spiro[isobenzofuran-1(3h),9’-[9h]xanthen]-3-one,4,5,6,7-tetrachloro-3’,6’-dihy
  • ROSE BENGAL LACTONE
  • 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one
  • 2,4,5,7-Tetraiodo-3,6-dihydroxy-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
  • 3,6-Dihydroxy-2,4,5,7-tetraiodo-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
  • 4',5',6',7'-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
  • Solvent Red 141
  • 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[2-benzofuran-3,9'-xanthene]-1-one
  • C.I.Solvent Red 141:C.I.45440:1
  • 4,5,6,7-Tetrachloro-2’,4’,5’,7’-tetraiodofluorescein
  • 4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
  • 4159-77-7
  • C20H4Cl4I4O5
  • Q-R
  • Stains and Dyes
  • Stains&Dyes, A to