ROSE BENGAL LACTONE

Product Name: ROSE BENGAL LACTONE
CAS No.: 4159-77-7
Chemical Name: ROSE BENGAL LACTONE
Synonyms: Solvent Red 141;ROSE BENGAL LACTONE;4’,5’,7’-tetraiodo-droxy-2;C.I.Solvent Red 141:C.I.45440:1;4,5,6,7-Tetrachloro-2’,4’,5’,7’-tetraiodofluorescein;spiro[isobenzofuran-1(3h),9’-[9h]xanthen]-3-one,4,5,6,7-tetrachloro-3’,6’-dihy;4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[2-benzofuran-3,9'-xanthene]-1-one;4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one;4',5',6',7'-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one;3,6-Dihydroxy-2,4,5,7-tetraiodo-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one
CBNumber: CB8331887
Molecular Formula: C20H4Cl4I4O5
Formula Weight: 973.67
MOL File: 4159-77-7.mol

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ROSE BENGAL LACTONE Property

Melting point:: 280 °C (dec.)(lit.)
storage temp.: room temp
Boiling point:: 741.8±60.0 °C(Predicted)
Density: 2.96±0.1 g/cm3(Predicted)
pka: 7.03±0.20(Predicted)
form: powder
color: pink to red
λmax: 557 nm
ε(extinction coefficient): ≥10000 at 317-323nm
≥30000 at 516-522nm
≥95000 at 554-560nm
EPA Substance Registry System: Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo- (4159-77-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 328960
Product name: Rose Bengal lactone
Purity: 95%
Packaging: 1g
Price: $116
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: DYE0000553
Product name: ROSE BENGAL LACTONE
Purity: 95.00%
Packaging: 1G
Price: $626.43
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: DYE0000553
Product name: ROSE BENGAL LACTONE
Purity: 95.00%
Packaging: 5G
Price: $1163.45
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: DYE0000553
Product name: ROSE BENGAL LACTONE
Purity: 95.00%
Packaging: 10G
Price: $1765.08
Updated: 2021/12/16

Chem-Impex

Product number: 42054
Product name: RoseBengallactone,≥94%(HPLC),suitableforHematology&Histology
Purity: ≥94%(HPLC)
Packaging: 1G
Price: $95.51
Updated: 2021/12/16

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ROSE BENGAL LACTONE Chemical Properties,Usage,Production

Description

Rose bengal lactone is a potent inhibitor of human metabolism that binds to the proteasome pathway and inhibits the polymerization of tubulin. It has been shown to bind with high affinity to microtubules and inhibit their assembly, which leads to cell death. Rose bengal lactone also binds with high affinity to potassium ion, which may contribute to its anti-cancer effects. This compound has also been found to be an effective inhibitor of goiters in rats by binding with aliphatic hydrocarbons such as cholesterol.

Chemical Properties

Bluish-pink powder. Soluble in water.

Uses

Biological stain; colorant for inks, cellulosics, foods, cosmetics, medicine (diagnostic aid).

Preparation

will Resorcinol and 4,5,6,7-Tetrachloroisobenzofuran-1,3-dione condensation, The resulting 4,5,6,7 – tetrachloro-fluorescein tetraiodide.

Properties and Applications

blue light red. Soluble in water for blue light yellow, no fluorescence, in concentrated sulfuric acid for brown, dilution after hot pink precipitation. Used in cosmetics coloring.

Standard	Light Fastness	Heat-resistant(℃)		water	Sodium Carbonate(5%)	Hydrochloric acid(5%)
		Melting point	Stable
ISO	Poor			Insoluble

ROSE BENGAL LACTONE Preparation Products And Raw materials

Raw materials

Preparation Products

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ROSE BENGAL LACTONE Suppliers

China 12 Switzerland 1 United Kingdom 1 United States 9 Global 23

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20806
Advantage: 60

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 10007
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-0371-55055611 18137792234
Fax: QQ：3002694073
Email: 3002694073@qq.com
Country: China
ProdList: 10349
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49476
Advantage: 58

Shanghai Universal Biotech Co.,Ltd

Tel: 13774214275
Email: zhouzz@univ-bio.com
Country: China
ProdList: 24998
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: SY06@accelachem.com
Country: China
ProdList: 8256
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 13308200041
Email: 2851167782@qq.com
Country: China
ProdList: 11183
Advantage: 58

4159-77-7, ROSE BENGAL LACTONERelated Search:

Solvent Red 127 Agar rose bengal Solvent Red 132 Solvent Red 13 ERYTHROSIN B Disperse Red 1 Solvent Red 135 SOLVENT RED 130 Solvent Red 100 Solvent Red 138 ROSE BENGAL ROSE BENGAL ROSE BENGAL LACTONE ROSE BENGAL DIACETATE ROSE BENGAL, BIS[TRI(N-BUTYL)] AMMONIUM SALT ROSE BENGAL, BENZYL ESTER ROSE BENGAL, ETHYL ESTER ROSE BENGAL, METHYL ESTER

4’,5’,7’-tetraiodo-droxy-2

spiro[isobenzofuran-1(3h),9’-[9h]xanthen]-3-one,4,5,6,7-tetrachloro-3’,6’-dihy

ROSE BENGAL LACTONE

4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3-one

2,4,5,7-Tetraiodo-3,6-dihydroxy-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one

3,6-Dihydroxy-2,4,5,7-tetraiodo-4',5',6',7'-tetrachlorospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one

4',5',6',7'-Tetrachloro-3,6-dihydroxy-2,4,5,7-tetraiodospiro[9H-xanthene-9,1'(3'H)-isobenzofuran]-3'-one

Solvent Red 141

4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodospiro[2-benzofuran-3,9'-xanthene]-1-one

C.I.Solvent Red 141:C.I.45440:1

4,5,6,7-Tetrachloro-2’,4’,5’,7’-tetraiodofluorescein

4,5,6,7-Tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one

4159-77-7

C20H4Cl4I4O5

Q-R

Stains and Dyes

Stains&Dyes, A to