Avarofloxacin hydrochloride

Product Name: Avarofloxacin hydrochloride
CAS No.: 1001162-01-1
Chemical Name: Avarofloxacin hydrochloride
Synonyms: JNJ-Q2 HCl;JNJ-32729463;JNJ 32729463;Acorafloxacin HCl;JNJ-Q2 hydrochloride;Avarofloxacin hydrochloride;Acorafloxacin hydrochloride
CBNumber: CB83333710
Molecular Formula: C21H24ClF2N3O4
Formula Weight: 455.8827664
MOL File: 1001162-01-1.mol

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Avarofloxacin hydrochloride Chemical Properties,Usage,Production

Uses

Acorafloxacin hydrochloride (JNJ-Q2 hydrochloride) is a broad-spectrum fluoroquinolone anti-bacterial drug being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia[1]. Acorafloxacin hydrochloride (Avarofloxacin ) is an aminoethylidenylpiperidine fluoroquinolone that demonstrates antibacterial effect against numerous Gram-positive bacteria with a mean 0.12 mg/L MIC90 value[2]. Acorafloxacin hydrochloride (JNJ-Q2) has potential for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections[3].

References

[1] Jones TM, et al. Focus on JNJ-Q2, a novel fluoroquinolone, for the management of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections. DOI:10.2147/IDR.S105620
[2] Kocsis B, et al. Chemical structure and pharmacokinetics of novel quinolone agents represented by avarofloxacin, delafloxacin, finafloxacin, zabofloxacin and nemonoxacin. Ann Clin Microbiol Antimicrob. 2016 May 23;15(1):34. DOI:10.1186/s12941-016-0150-4
[3] Farrell DJ, et al. JNJ-Q2, a new fluoroquinolone with potent in vitro activity against Staphylococcus aureus, including methicillin- and fluoroquinolone-resistant strains. Antimicrob Agents Chemother. 2011 Jul;55(7):3631-4. DOI:10.1128/AAC.00162-11

Avarofloxacin hydrochloride Preparation Products And Raw materials

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Avarofloxacin hydrochloride Suppliers

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1001162-01-1, Avarofloxacin hydrochlorideRelated Search:

Avarofloxacin hydrochloride

Acorafloxacin HCl

Acorafloxacin hydrochloride

JNJ 32729463

JNJ-32729463

JNJ-Q2 HCl

JNJ-Q2 hydrochloride

1001162-01-1