2'-O-Methyl-N2-methylguanosine

Product Name: 2'-O-Methyl-N2-methylguanosine
CAS No.: 135023-21-1
Chemical Name: 2'-O-Methyl-N2-methylguanosine
Synonyms: N2,2'-O-dimethylguanosine;N-methyl-2'-O-methylGuanosine;2’-O-Methyl-N2-methylguanosine;2'-O-Methyl-N2-methylguanosine;Guanosine, N-methyl-2'-O-methyl-;2’-O-Methyl-N2-methylguanosine,RNA-modified nucleoside m2Gm;9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2-(methylamino)-1,9-dihydro-6H-purin-6-one
CBNumber: CB83334227
Molecular Formula: C12H17N5O5
Formula Weight: 311.29
MOL File: 135023-21-1.mol

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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2'-O-Methyl-N2-methylguanosine Chemical Properties,Usage,Production

Uses

N2,2'-O-Dimethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

2'-O-Methyl-N2-methylguanosine Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-O-Methyl-N2-methylguanosine Suppliers

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135023-21-1, 2'-O-Methyl-N2-methylguanosineRelated Search:

2'-O-Methyl-N2-methylguanosine

Guanosine, N-methyl-2'-O-methyl-

N2,2'-O-dimethylguanosine

9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2-(methylamino)-1,9-dihydro-6H-purin-6-one

2’-O-Methyl-N2-methylguanosine,RNA-modified nucleoside m2Gm

N-methyl-2'-O-methylGuanosine

2’-O-Methyl-N2-methylguanosine

135023-21-1