ChemicalBook > CAS DataBase List > 5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine
5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine
- Product Name
- 5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine
- CAS No.
- 2305415-77-2
- Chemical Name
- 5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine
- Synonyms
- 5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine;5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine;5-(azidomethyl)-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
- CBNumber
- CB83334272
- Molecular Formula
- C13H19N5O7
- Formula Weight
- 357.32
- MOL File
- 2305415-77-2.mol
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5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine Chemical Properties,Usage,Production
Uses
5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. 5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
References
[1] Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. DOI:10.3390/molecules16097980
5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine Preparation Products And Raw materials
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