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5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine

Product Name
5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine
CAS No.
2305415-77-2
Chemical Name
5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine
Synonyms
5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine;5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine;5-(azidomethyl)-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CBNumber
CB83334272
Molecular Formula
C13H19N5O7
Formula Weight
357.32
MOL File
2305415-77-2.mol
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Hazard and Precautionary Statements (GHS)

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5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine Chemical Properties,Usage,Production

Uses

5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. 5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

References

[1] Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. DOI:10.3390/molecules16097980

5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine Preparation Products And Raw materials

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Preparation Products

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2305415-77-2, 5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridineRelated Search:


  • 5-(Azidomethyl)-2'-O-(2-methoxyethyl)uridine
  • 5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine
  • 5-(azidomethyl)-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
  • 2305415-77-2