ChemicalBook > CAS DataBase List > Liafensine
Liafensine
- Product Name
- Liafensine
- CAS No.
- 1198790-53-2
- Chemical Name
- Liafensine
- Synonyms
- BMS-820836;Liafensine;3-Pyridazinamine, 6-[(4S)-1,2,3,4-tetrahydro-2-methyl-4-(2-naphthalenyl)-7-isoquinolinyl]-
- CBNumber
- CB83354243
- Molecular Formula
- C24H22N4
- Formula Weight
- 366.46
- MOL File
- 1198790-53-2.mol
More
Less
Liafensine Property
- Boiling point:
- 617.1±55.0 °C(Predicted)
- Density
- 1.223±0.06 g/cm3(Predicted)
- pka
- 7.42±0.40(Predicted)
More
Less
Liafensine Chemical Properties,Usage,Production
Uses
Liafensine (BMS-820836) is a triple monoamine reuptake inhibitor (TRI), that inhibits dopamine transporter, serotonin transporter and norepinephrine transporter, with IC50s of 5.67, 1.08 and 7.99 nM, respectively. Liafensine exhibits antidepressant activity[1].
Definition
ChEBI: Liafensine is a member of isoquinolines.
References
[1] Risinger R, et al., Evaluation of safety and tolerability, pharmacokinetics, and pharmacodynamics of BMS-820836 in healthy subjects: a placebo-controlled, ascending single-dose study. Psychopharmacology (Berl). 2014 Jun;231(11):2299-310. DOI:10.1007/s00213-013-3391-3
Liafensine Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
Liafensine Suppliers
- Tel
- 010-88886666-01 13112345678
- Fax
- CDXH21@126.com
- loyson@tcypharm.com
- Country
- China
- ProdList
- 597
- Advantage
- 55
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
- Country
- China
- ProdList
- 11973
- Advantage
- 58
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 29423
- Advantage
- 58
- Tel
- 400-821-026
- Sales@sangon.com
- Country
- China
- ProdList
- 6710
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58