Biotin-PEG3-CH2COOH

Product Name: Biotin-PEG3-CH2COOH
CAS No.: 1189560-96-0
Chemical Name: Biotin-PEG3-CH2COOH
Synonyms: CAS_1189560-96-0;Biotin-PEG3-CH2COOH;Biotin-PEG?-CH?COOH;Biotin-PEG3-acetic Acid;11-(Biotinamido)-3,6,9-trioxaundecanoic Acid;13-oxo-17-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecanoic acid;3,6,9-Trioxa-12-azaheptadecanoic acid, 17-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-13-oxo-;13-oxo-17-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecan-1-oic acid;2-{2-[2-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}ethoxy)ethoxy]ethoxy}acetic acid;Biotin-PEG3-CH2COOH/3,6,9-Trioxa-12-azaheptadecanoic acid, 17-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-13-oxo-
CBNumber: CB83354304
Molecular Formula: C18H31N3O7S
Formula Weight: 433.52
MOL File: 1189560-96-0.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Acrotein

Product number: B-1365
Product name: Biotin-PEG3-CH2COOH
Purity: 97%
Packaging: 0.5g
Price: $366.7
Updated: 2021/12/16

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Biotin-PEG3-CH2COOH Chemical Properties,Usage,Production

Biological Activity

Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Biotin-PEG3-CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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Biotin-PEG3-CH2COOH Suppliers

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1189560-96-0, Biotin-PEG3-CH2COOHRelated Search:

Biotinyl-AEEA Biotin-PEG4-NH2 HCl Biotin-PEG5-Amine Biotin-PEG20000-maleimide 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester Biotin-PEG5-SH Biotin-PEG3-propargyl

Biotin-PEG3-acetic Acid

13-oxo-17-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecanoic acid

Biotin-PEG3-CH2COOH

CAS_1189560-96-0

3,6,9-Trioxa-12-azaheptadecanoic acid, 17-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-13-oxo-

11-(Biotinamido)-3,6,9-trioxaundecanoic Acid

13-oxo-17-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecan-1-oic acid

Biotin-PEG3-CH2COOH/3,6,9-Trioxa-12-azaheptadecanoic acid, 17-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-13-oxo-

Biotin-PEG?-CH?COOH

2-{2-[2-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}ethoxy)ethoxy]ethoxy}acetic acid

1189560-96-0

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