ChemicalBook > CAS DataBase List > RO 5028442

RO 5028442

Product Name
RO 5028442
CAS No.
920022-47-5
Chemical Name
RO 5028442
Synonyms
RG7713;RO 5028442;RO5028442, >98%;RO 5028442 (RG7713);RG7713, 10 mM in DMSO;RO-5028442; RO 5028442; RO5028442;RG-7713,Inhibitor,RO5028442,RG7713,RO-5028442,RG 7713,Vasopressin Receptor,inhibit;(6-chloro-1-(2-(dimethylamino)ethyl)-1H-indol-3-yl)(3H-spiro[isobenzofuran-1,4'-piperidin]-1'-yl)methanone;Methanone, [6-chloro-1-[2-(dimethylamino)ethyl]-1H-indol-3-yl]spiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl-
CBNumber
CB83355316
Molecular Formula
C25H28ClN3O2
Formula Weight
437.96
MOL File
920022-47-5.mol
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RO 5028442 Property

Boiling point:
621.3±55.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Chloroform: 10 mg/ml
form 
A crystalline solid
pka
9.27±0.28(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

ChemScene
Product number
CS-7944
Product name
RG7713
Purity
99.79%
Packaging
1mg
Price
$70
Updated
2021/12/16
ChemScene
Product number
CS-7944
Product name
RG7713
Purity
99.79%
Packaging
5mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-7944
Product name
RG7713
Purity
99.79%
Packaging
10mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-7944
Product name
RG7713
Purity
99.79%
Packaging
50mg
Price
$750
Updated
2021/12/16
ChemScene
Product number
CS-7944
Product name
RG7713
Purity
99.79%
Packaging
100mg
Price
$1200
Updated
2021/12/16
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RO 5028442 Chemical Properties,Usage,Production

Uses

RG7713 (RO5028442) is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM (hV1a) and 39 nM (mV1a).

References

[1] Ratni H, et al. Discovery of highly selective brain-penetrant vasopressin 1a antagonists for the potential treatment of autism via a chemogenomic and scaffold hopping approach. J Med Chem. 2015 Mar 12;58(5):2275-89. DOI:10.1021/jm501745f

RO 5028442 Preparation Products And Raw materials

Raw materials

Preparation Products

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RO 5028442 Suppliers

Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
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55
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4827
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
7999
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62
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9550
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58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Medi-tech Bioscientific Co., Ltd.
Tel
0519-83246372 13585352506
Fax
0519-83246372
Country
China
ProdList
1844
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58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19552
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Wuxi Donghe Pharmaceutical Technology Co., Ltd.
Tel
63313187 15358055255
Fax
QQ:63313187
Email
63313187@qq.com
Country
China
ProdList
1985
Advantage
58

920022-47-5, RO 5028442Related Search:


  • RG7713
  • RO-5028442; RO 5028442; RO5028442
  • RO 5028442
  • RO5028442, >98%
  • Methanone, [6-chloro-1-[2-(dimethylamino)ethyl]-1H-indol-3-yl]spiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl-
  • RG-7713,Inhibitor,RO5028442,RG7713,RO-5028442,RG 7713,Vasopressin Receptor,inhibit
  • (6-chloro-1-(2-(dimethylamino)ethyl)-1H-indol-3-yl)(3H-spiro[isobenzofuran-1,4'-piperidin]-1'-yl)methanone
  • RO 5028442 (RG7713)
  • RG7713, 10 mM in DMSO
  • 920022-47-5