ChemicalBook > CAS DataBase List > RO 5028442
RO 5028442
- Product Name
- RO 5028442
- CAS No.
- 920022-47-5
- Chemical Name
- RO 5028442
- Synonyms
- RG7713;RO 5028442;RO5028442, >98%;RO 5028442 (RG7713);RG7713, 10 mM in DMSO;RO-5028442; RO 5028442; RO5028442;RG-7713,Inhibitor,RO5028442,RG7713,RO-5028442,RG 7713,Vasopressin Receptor,inhibit;(6-chloro-1-(2-(dimethylamino)ethyl)-1H-indol-3-yl)(3H-spiro[isobenzofuran-1,4'-piperidin]-1'-yl)methanone;Methanone, [6-chloro-1-[2-(dimethylamino)ethyl]-1H-indol-3-yl]spiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl-
- CBNumber
- CB83355316
- Molecular Formula
- C25H28ClN3O2
- Formula Weight
- 437.96
- MOL File
- 920022-47-5.mol
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RO 5028442 Property
- Boiling point:
- 621.3±55.0 °C(Predicted)
- Density
- 1.28±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Chloroform: 10 mg/ml
- form
- A crystalline solid
- pka
- 9.27±0.28(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-7944
- Product name
- RG7713
- Purity
- 99.79%
- Packaging
- 1mg
- Price
- $70
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-7944
- Product name
- RG7713
- Purity
- 99.79%
- Packaging
- 5mg
- Price
- $150
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-7944
- Product name
- RG7713
- Purity
- 99.79%
- Packaging
- 10mg
- Price
- $250
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-7944
- Product name
- RG7713
- Purity
- 99.79%
- Packaging
- 50mg
- Price
- $750
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-7944
- Product name
- RG7713
- Purity
- 99.79%
- Packaging
- 100mg
- Price
- $1200
- Updated
- 2021/12/16
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RO 5028442 Chemical Properties,Usage,Production
Uses
RG7713 (RO5028442) is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM (hV1a) and 39 nM (mV1a).
References
[1] Ratni H, et al. Discovery of highly selective brain-penetrant vasopressin 1a antagonists for the potential treatment of autism via a chemogenomic and scaffold hopping approach. J Med Chem. 2015 Mar 12;58(5):2275-89. DOI:10.1021/jm501745f
RO 5028442 Preparation Products And Raw materials
Raw materials
Preparation Products
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