ChemicalBook > CAS DataBase List > (S)-2-(6,7-DIHYDRO-5H-THIAZOLO[4,5-F]INDOL-2-YL)-4,5-DIHYDROTHIAZOLE-4-CARBOXYLIC ACID

(S)-2-(6,7-DIHYDRO-5H-THIAZOLO[4,5-F]INDOL-2-YL)-4,5-DIHYDROTHIAZOLE-4-CARBOXYLIC ACID

Product Name: (S)-2-(6,7-DIHYDRO-5H-THIAZOLO[4,5-F]INDOL-2-YL)-4,5-DIHYDROTHIAZOLE-4-CARBOXYLIC ACID
CAS No.: 1247879-16-8
Chemical Name: (S)-2-(6,7-DIHYDRO-5H-THIAZOLO[4,5-F]INDOL-2-YL)-4,5-DIHYDROTHIAZOLE-4-CARBOXYLIC ACID
Synonyms: CYCLUC1;Luciferase substrate;CycLuc1, 10 mM in DMSO;CycLuc1(Luciferase substrate);Luciferase Substrate, CycLuc1;CycLuc 1,inhibit,CycLuc1,Reactive Oxygen Species,Inhibitor,CycLuc-1;(S)-2-(6,7-DIHYDRO-5H-THIAZOLO[4,5-F]INDOL-2-YL)-4,5-DIHYDROTHIAZOLE-4-CARBOXYLIC ACID;CycLuc1 (R)-2-(6,7-dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole- 4-carboxylic acid;4-Thiazolecarboxylic acid, 2-(6,7-dihydro-5H-pyrrolo[3,2-f]benzothiazol-2-yl)-4,5-dihydro-, (4S)-;Cyluc1 [(4S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydro-thiazole-4-carboxylic acid]
CBNumber: CB83358296
Molecular Formula: C13H11N3O2S2
Formula Weight: 305.38
MOL File: 1247879-16-8.mol

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(S)-2-(6,7-DIHYDRO-5H-THIAZOLO[4,5-F]INDOL-2-YL)-4,5-DIHYDROTHIAZOLE-4-CARBOXYLIC ACID Property

Boiling point:: 606.8±65.0 °C(Predicted)
Density: 1.84±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 83.33 mg/mL (272.87 mM)
pka: 3.54±0.20(Predicted)
form: Solid
color: Yellow to brown

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 5.30650
Product name: Luciferase Substrate, CycLuc1
Packaging: 10mg
Price: $321
Updated: 2025/07/31

Tocris

Product number: 6823
Product name: CycLuc1
Purity: ≥98%(HPLC)
Packaging: 5
Price: $118
Updated: 2021/12/16

ChemScene

Product number: CS-0089228
Product name: CycLuc1
Purity: 98.15%
Packaging: 10mg
Price: $80
Updated: 2021/12/16

ChemScene

Product number: CS-0089228
Product name: CycLuc1
Purity: 98.15%
Packaging: 25mg
Price: $160
Updated: 2021/12/16

ChemScene

Product number: CS-0089228
Product name: CycLuc1
Purity: 98.15%
Packaging: 50mg
Price: $280
Updated: 2021/12/16

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(S)-2-(6,7-DIHYDRO-5H-THIAZOLO[4,5-F]INDOL-2-YL)-4,5-DIHYDROTHIAZOLE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

Luciferase Substrate, CycLuc1 has been used for transfecting HEK293 cells to study the inhibition of intracellular luciferase crystallization by D-luciferin and its synthetic analogues.

Biological Activity

Cell permeable: yes', 'Primary Target
Luciferase

in vivo

CycLuc1 (0.05-5 mM, intraperitoneally injected) can improve bioluminescence imaging (BLI) of the existing luciferase reporter protein in mice and achieve brain imaging that D-luciferin cannot achieve^[2].

Animal Model:	Mouse xenograft tumor models^[2]
Dosage:	0.05, 0.5, 1, 5 mM, 100 μL
Administration:	i.p.
Result:	Yielded a >10-fold higher bioluminescent signal than could be obtained from D-luciferin injection at equivalent doses.

storage

Store at -20°C

(S)-2-(6,7-DIHYDRO-5H-THIAZOLO[4,5-F]INDOL-2-YL)-4,5-DIHYDROTHIAZOLE-4-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-2-(6,7-DIHYDRO-5H-THIAZOLO[4,5-F]INDOL-2-YL)-4,5-DIHYDROTHIAZOLE-4-CARBOXYLIC ACID Suppliers

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1247879-16-8, (S)-2-(6,7-DIHYDRO-5H-THIAZOLO[4,5-F]INDOL-2-YL)-4,5-DIHYDROTHIAZOLE-4-CARBOXYLIC ACIDRelated Search:

(S)-2-(6,7-DIHYDRO-5H-THIAZOLO[4,5-F]INDOL-2-YL)-4,5-DIHYDROTHIAZOLE-4-CARBOXYLIC ACID

Cyluc1 [(4S)-2-(6,7-Dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydro-thiazole-4-carboxylic acid]

CycLuc1(Luciferase substrate)

CYCLUC1

Luciferase substrate

4-Thiazolecarboxylic acid, 2-(6,7-dihydro-5H-pyrrolo[3,2-f]benzothiazol-2-yl)-4,5-dihydro-, (4S)-

CycLuc1 (R)-2-(6,7-dihydro-5H-thiazolo[4,5-f]indol-2-yl)-4,5-dihydrothiazole- 4-carboxylic acid

CycLuc 1,inhibit,CycLuc1,Reactive Oxygen Species,Inhibitor,CycLuc-1

Luciferase Substrate, CycLuc1

CycLuc1, 10 mM in DMSO

1247879-16-8