ChemicalBook > CAS DataBase List > Benzyloxy carbonyl-PEG3-t-butyl ester
Benzyloxy carbonyl-PEG3-t-butyl ester
- Product Name
- Benzyloxy carbonyl-PEG3-t-butyl ester
- CAS No.
- 1835759-86-8
- Chemical Name
- Benzyloxy carbonyl-PEG3-t-butyl ester
- Synonyms
- Benzyloxy carbonyl-PEG3-C2-Boc;Benzyloxy carbonyl-PEG3-t-butyl ester;benzyl 3-[2-[2-(3-tert-butoxy-3-oxo-propoxy)ethoxy]ethoxy]propanoate;4,7,10,14-Tetraoxahexadecanoic acid, 15,15-dimethyl-13-oxo-, phenylmethyl ester
- CBNumber
- CB83363865
- Molecular Formula
- C21H32O7
- Formula Weight
- 396.47
- MOL File
- 1835759-86-8.mol
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Benzyloxy carbonyl-PEG3-t-butyl ester Property
- Boiling point:
- 476.1±35.0 °C(Predicted)
- Density
- 1.092±0.06 g/cm3(Predicted)
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-22927
- Product name
- Benzyloxycarbonyl-PEG3-t-butylester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $260
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22927
- Product name
- Benzyloxycarbonyl-PEG3-t-butylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $450
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22927
- Product name
- Benzyloxycarbonyl-PEG3-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $680
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22927
- Product name
- Benzyloxycarbonyl-PEG3-t-butylester
- Purity
- 98%
- Packaging
- 1g
- Price
- $1100
- Updated
- 2021/12/16
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Benzyloxy carbonyl-PEG3-t-butyl ester Chemical Properties,Usage,Production
Description
Benzyloxy carbonyl-PEG3-t-butyl ester is a PEG linker containing a benzyloxy carbonyl group and a t-butyl ester protecting group. The benzyloxy carbonyl helps to enhance chemoselectivity of a reaction. The t-butyl ester can be removed under acidic conditions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Uses
Benzyloxy carbonyl-PEG3-C2-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Benzyloxy carbonyl-PEG3-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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