ChemicalBook > CAS DataBase List > TLR7-IN-1
TLR7-IN-1
- Product Name
- TLR7-IN-1
- CAS No.
- 1642857-69-9
- Chemical Name
- TLR7-IN-1
- Synonyms
- CS-2748;TLR7-IN-1;TLR7 agonist 2;TLR7-agonist-1;TLR7 agonist 2, 10 mM in DMSO;inhibit,TLR7 agonist 2,TLR-7 agonist 2,Inhibitor,Toll-like Receptor (TLR);5H-Pyrrolo[3,2-d]pyrimidin-2-amine, 4-[(5-methyl-3-isoxazolyl)methoxy]-5-(2-pyridinylmethyl)-;4-[(5-methyl-1,2-oxazol-3-yl)methoxy]-5-[(pyridin-2-yl)methyl]-5H-pyrrolo[3,2-d]pyrimidin-2-amine
- CBNumber
- CB83364145
- Molecular Formula
- C17H16N6O2
- Formula Weight
- 336.35
- MOL File
- 1642857-69-9.mol
More
Less
TLR7-IN-1 Property
- Melting point:
- 147 - 149°C
- Boiling point:
- 655.1±65.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 6.89±0.30(Predicted)
- form
- Solid
- color
- White to Off-White
More
Less
N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 28450
- Product name
- TLR7 Agonist 2
- Packaging
- 1mg
- Price
- $121
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28450
- Product name
- TLR7 Agonist 2
- Packaging
- 10mg
- Price
- $841
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28450
- Product name
- TLR7 Agonist 2
- Packaging
- 5mg
- Price
- $481
- Updated
- 2024/03/01
TRC
- Product number
- T426520
- Product name
- TLR7-agonist-1
- Packaging
- 2.5mg
- Price
- $1320
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0023485
- Product name
- TLR7agonist2
- Purity
- 99.25%
- Packaging
- 1mg
- Price
- $210
- Updated
- 2021/12/16
More
Less
TLR7-IN-1 Chemical Properties,Usage,Production
Uses
TLR7-agonist-1, is a potent and selective Toll-like Receptor 7 (TLR7) agonist with a LEC of 0.4 μM.
in vivo
TLR7 agonist 2 is found to be rapidly cleared in conjunction with our target profile. Both Cmax and AUC increase less than dose proportionally between 0.3 and 3 mg/kg and more than dose-proportionally between 3 and 10 mg/kg. TLR7 agonist 2 can induce an antiviral interferon stimulated gene (ISG) response without inducing an IFNα response at a low dose. TLR7 agonist 2 also induces a 2.7 log decrease in serum HBV viral load from 0.3 mg/kg, and a maximum 3.1 log decrease is observed for doses between 1 and 5 mg/kg[1].
TLR7-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
TLR7-IN-1 Suppliers
- Tel
- 021-52996696，15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
- ProdList
- 4817
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 86249
- Advantage
- 60
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8000
- Advantage
- 62
- Tel
- 010-50973130 18101056239
- 3193328036@qq.com
- Country
- China
- ProdList
- 29661
- Advantage
- 68
- Tel
- 021-58111628 15800915896
- Fax
- QQ 3285589261
- sales@twochem.com
- Country
- China
- ProdList
- 1788
- Advantage
- 58
- Tel
- 17317130613
- Fax
- QQ3358272972
- 3358272972@qq.com
- Country
- China
- ProdList
- 3291
- Advantage
- 58
- Tel
- 15911056312
- liming@bio-fount.com
- Country
- China
- ProdList
- 9729
- Advantage
- 58
- Tel
- 021-50676523 18019098996
- info@acelybio.com
- Country
- China
- ProdList
- 3960
- Advantage
- 58
- Tel
- 18081075745
- chemflowtech@sina.com
- Country
- China
- ProdList
- 1886
- Advantage
- 58