tert-butyl hex-5-ynoate

Product Name: tert-butyl hex-5-ynoate
CAS No.: 73448-14-3
Chemical Name: tert-butyl hex-5-ynoate
Synonyms: tert-Butyl 5-Hexynoate;tert-butyl hex-5-ynoate;5-Hexynoic acid tert-butyl ester;hex-5-ynoic acid tert-butyl ester;Tert-butyl hex-5-ynoate - [B70772];5-Hexynoic acid, 1,1-dimethylethyl ester
CBNumber: CB83364978
Molecular Formula: C10H16O2
Formula Weight: 168.23
MOL File: 73448-14-3.mol

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tert-butyl hex-5-ynoate Property

Boiling point:: 209.7±23.0 °C(Predicted)
Density: 0.929±0.06 g/cm3(Predicted)
form: Liquid

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Hazard and Precautionary Statements (GHS)

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tert-butyl hex-5-ynoate Chemical Properties,Usage,Production

Uses

tert-Butyl hex-5-ynoate is the linker that can be used for PROTAC synthesis of PROTAC cGAS degrader-1 (HY-172208)[1].

References

[1] He P, et al., Discovery of a Novel CRBN-Recruiting cGAS PROTAC Degrader for the Treatment of Ulcerative Colitis. J Med Chem. 2025 Mar 13;68(5):5551-5572. DOI:10.1021/acs.jmedchem.4c02774

tert-butyl hex-5-ynoate Preparation Products And Raw materials

Raw materials

Preparation Products

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73448-14-3, tert-butyl hex-5-ynoateRelated Search:

tert-butyl hex-5-ynoate

hex-5-ynoic acid tert-butyl ester

5-Hexynoic acid tert-butyl ester

5-Hexynoic acid, 1,1-dimethylethyl ester

tert-Butyl 5-Hexynoate

Tert-butyl hex-5-ynoate - [B70772]

73448-14-3