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Protein kinase inhibitors 1

Product Name
Protein kinase inhibitors 1
CAS No.
1365986-44-2
Chemical Name
Protein kinase inhibitors 1
Synonyms
CVM-6-139-1;HIPK2 inhibitor;Reaxys ID: 21909876;Protein kinase inhibitors 1;A64 trifluoroacetate >=98% (HPLC);2,4-Thiazolidinedione, 5-[[1,2-dihydro-2-oxo-6'-(1-piperazinyl)[3,3'-bipyridin]-5-yl]methylene]-;5-{[2-oxo-6'-(piperazin-1-yl)-1,2-dihydro-[3,3'-bipyridin]-5-yl]methylidene}-1,3-thiazolidine-2,4-dione
CBNumber
CB83379981
Molecular Formula
C18H17N5O3S
Formula Weight
383.42
MOL File
1365986-44-2.mol
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Protein kinase inhibitors 1 Property

Density 
1.487±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
5.58±0.20(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0035384
Product name
Proteinkinaseinhibitors1
Purity
≥99.0%
Packaging
5mg
Price
$80
Updated
2021/12/16
ChemScene
Product number
CS-0035384
Product name
Proteinkinaseinhibitors1
Purity
≥99.0%
Packaging
10mg
Price
$140
Updated
2021/12/16
ChemScene
Product number
CS-0035384
Product name
Proteinkinaseinhibitors1
Purity
≥99.0%
Packaging
25mg
Price
$310
Updated
2021/12/16
DC Chemicals
Product number
DC10898
Product name
HIPK2inhibitor
Purity
>98%
Packaging
100mg
Price
$600
Updated
2021/12/16
DC Chemicals
Product number
DC10898
Product name
HIPK2inhibitor
Purity
>98%
Packaging
250mg
Price
$1100
Updated
2021/12/16
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Protein kinase inhibitors 1 Chemical Properties,Usage,Production

Uses

Protein kinase inhibitor 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.

References

[1] Miduturu CV, et al. High-throughput kinase profiling: a more efficient approach toward the discovery of new kinaseinhibitors. Chem Biol. 2011 Jul 29;18(7):868-79. DOI:10.1016/j.chembiol.2011.05.010

Protein kinase inhibitors 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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1365986-44-2, Protein kinase inhibitors 1Related Search:


  • Protein kinase inhibitors 1
  • HIPK2 inhibitor
  • Reaxys ID: 21909876
  • 2,4-Thiazolidinedione, 5-[[1,2-dihydro-2-oxo-6'-(1-piperazinyl)[3,3'-bipyridin]-5-yl]methylene]-
  • A64 trifluoroacetate >=98% (HPLC)
  • CVM-6-139-1
  • 5-{[2-oxo-6'-(piperazin-1-yl)-1,2-dihydro-[3,3'-bipyridin]-5-yl]methylidene}-1,3-thiazolidine-2,4-dione
  • 1365986-44-2