Evocalcet

Product Name: Evocalcet
CAS No.: 870964-67-3
Chemical Name: Evocalcet
Synonyms: MT4580;MT 4580;Ivocase;Ivanka.;MT-4580;KHK7580;Evocalcet;Ivanka Sai;Evocase Impurity 2;Evocalcet, 10 mM in DMSO
CBNumber: CB83384772
Molecular Formula: C24H26N2O2
Formula Weight: 374.48
MOL File: 870964-67-3.mol

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Evocalcet Property

Boiling point:: 594.4±50.0 °C(Predicted)
Density: 1.23±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF:5.0(Max Conc. mg/mL);13.35(Max Conc. mM)
DMSO:5.0(Max Conc. mg/mL);13.35(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.81(Max Conc. mM)
form: A crystalline solid
pka: 4.71±0.10(Predicted)
color: White to off-white
InChI: InChI=1S/C24H26N2O2/c1-17(22-8-4-6-19-5-2-3-7-23(19)22)25-20-13-14-26(16-20)21-11-9-18(10-12-21)15-24(27)28/h2-12,17,20,25H,13-16H2,1H3,(H,27,28)/t17-,20+/m1/s1
InChIKey: RZNUIYPHQFXBAN-XLIONFOSSA-N
SMILES: C1(CC(O)=O)=CC=C(N2CC[C@H](N[C@@H](C3=C4C(C=CC=C4)=CC=C3)C)C2)C=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: N345665
Product name: 4-[(3S)-3-[[(1R)-1-(1-Naphthalenyl)ethyl]amino]-1-pyrrolidinyl]benzeneaceticAcid
Packaging: 25mg
Price: $725
Updated: 2021/12/16

ChemScene

Product number: CS-0014698
Product name: Evocalcet
Purity: 99.05%
Packaging: 5mg
Price: $80
Updated: 2021/12/16

ChemScene

Product number: CS-0014698
Product name: Evocalcet
Purity: 99.05%
Packaging: 10mg
Price: $120
Updated: 2021/12/16

ChemScene

Product number: CS-0014698
Product name: Evocalcet
Purity: 99.05%
Packaging: 50mg
Price: $450
Updated: 2021/12/16

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Evocalcet Chemical Properties,Usage,Production

Uses

4-[(3S)-3-[[(1R)-1-(1-Naphthalenyl)ethyl]amino]-1-pyrrolidinyl]benzeneacetic Acid is part of a pharmaceutical composition that is a therapeutic agent for hyperparathyroidism.

in vivo

Evocalcet (0.03 or 0.3 mg/kg; oral Administration, once) affects serum PTH and Ca levels^[1]. Evocalcet (0.3 mg/kg; oral Administration, once daily, for 5 weeks) reduces the serum PTH and Ca levels and increases the serum IP (inorganic phosphorus) level^[1].

Animal Model:	Male Sprague Dawley chronic kidney disease (CKD) rats with adenine induced secondary hyperparathyroidism (SHPT)^[1]
Dosage:	0.03 and 0.3 mg/kg
Administration:	Oral Administration; 0.03 and 0.3 mg/kg, once
Result:	Decreased the serum PTH and Ca levels at a dose of 0.3 mg/kg.

Evocalcet Preparation Products And Raw materials

Raw materials

Preparation Products

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Evocalcet Suppliers

China 100 India 1 United States 2 Global 103

Nanjing Jiusinuo Biomedical Technology Co., Ltd.

Tel: 18014830659
Email: njjsn2023@126.com
Country: China
ProdList: 244
Advantage: 58

Shengyang Runze (Beijing) Technology Co.,

Tel: 010-010-57302162 17611011830
Email: lyt001@syrz01.com
Country: China
ProdList: 180
Advantage: 58

Nanjing Weiyuan Biomedical Co., Ltd.

Tel: 17312961000
Email: syrz2020@gamil.com
Country: China
ProdList: 43
Advantage: 58

Nanjing JiuSiNuo Biopharmaceutical Technology Co., Ltd

Tel: 18851976882
Email: chensheng870628@126.com
Country: China
ProdList: 59
Advantage: 58

Nanjing webright Pharmaceutical Technology Co., Ltd

Tel: 18066048793; 18014498793
Email: 1504914633@qq.com
Country: China
ProdList: 1484
Advantage: 58

Synthetics China Co.,Ltd

Tel: 65218020 18248732722
Email: cliff.ji@pharmsyn.com
Country: China
ProdList: 99
Advantage: 60

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3505
Advantage: 58

Quality Control Solutions Ltd.

Tel: 0755-66853366 13670046396
Fax: 0755-28363542
Email: orders@qcsrm.com
Country: China
ProdList: 18422
Advantage: 56

Cangzhou Enke Pharma-tech Co., Ltd.

Tel: 0317-5296180 15533709196
Email: enkepharma@126.com;sale@enkepharma.com
Country: China
ProdList: 2335
Advantage: 55

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View Lastest Price from Evocalcet manufacturers

Guangzhou Tosun Pharmaceutical Ltd

Product: Evocalcet 870964-67-3
Price: US $0.00-0.00/kg
Min. Order: 5kg
Purity: 98%-102%
Supply Ability: 200kg
Release date: 2024-12-27

Shaanxi Dideu New Materials Co. Ltd

Product: Evocalcet 870964-67-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-11

870964-67-3, EvocalcetRelated Search:

Evocalcet

KHK7580

Benzeneacetic acid, 4-[(3S)-3-[[(1R)-1-(1-naphthalenyl)ethyl]amino]-1-pyrrolidinyl]-

2-{4-[(3S)-3-{[(1R)-1-(Naphthalen-1-yl)ethyl]amino}pyrrolidin-1-yl]phenyl}acetic acid

Calcium-sensing receptor,KHK-7580,Inhibitor,KHK 7580,CaSR,Evocalcet,inhibit

Ivocase

MT 4580

MT4580

MT-4580

Ivanka.

Evocalcet, 10 mM in DMSO

Ivanka Sai

Evocase Impurity 2

870964-67-3