ChemicalBook > CAS DataBase List > 1,3-DI-P-TOLYLCARBODIIMIDE

1,3-DI-P-TOLYLCARBODIIMIDE

Product Name
1,3-DI-P-TOLYLCARBODIIMIDE
CAS No.
726-42-1
Chemical Name
1,3-DI-P-TOLYLCARBODIIMIDE
Synonyms
SKL424;NSC 20627;DI-P-TOLY CARBODIIMIDE;di-p-tolylcarbodiimide;Bis(p-tolyl)carbodiimide;DI-PARA-TOLYLCARBODIIMIDE;N,N'-DI-P-TOLYLCARBODIMIDE;1,3-DI-P-TOLYLCARBODIIMIDE;N,N'-DI-P-TOLYLCARBODIIMIDE;1,3-Bis(p-tolyl)carbodiimide
CBNumber
CB8341183
Molecular Formula
C15H14N2
Formula Weight
222.29
MOL File
726-42-1.mol
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1,3-DI-P-TOLYLCARBODIIMIDE Property

Melting point:
56-58 °C (lit.)
Boiling point:
221-223 °C/20 mmHg (lit.)
Density 
1.1500
refractive index 
1.5000 (estimate)
storage temp. 
2-8°C
solubility 
soluble in diethyl ether, benzene, pyridine, t-butanol
form 
powder
Appearance
Off-white crystalline solid.
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0115382
Product name
1,3-DI-P-TOLYLCARBODIIMIDE
Purity
95.00%
Packaging
5G
Price
$1136.95
Updated
2021/12/16
AHH
Product number
MT-19614
Product name
N,N'-Di-p-tolylcarbodiimide
Purity
98%
Packaging
5g
Price
$338
Updated
2021/12/16
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1,3-DI-P-TOLYLCARBODIIMIDE Chemical Properties,Usage,Production

Uses

Reactant for synthesis of:

  • Cyclic guanidines
  • Five membered heterometallacycloallenes
  • Benzimidazoles or quinazolines via nucleophilic addition and intramolecular C-C bond formation
  • Benzoxazole and benzimidazole derivatives via cross-coupling reactions
  • Gem-difluorodihydrouracil derivatives via addition reactions

Reactant for ketene cycloadditions

Definition

ChEBI: A carbodiimide compound having a 4-methylphenyl substituent on both nitrogen atoms.

reaction suitability

reaction type: Coupling Reactions

Synthesis

Although tolyl carbodiimide is commercially available, it is quite expensive. It can be conveniently prepared from tolyl thiourea by oxidation with Mercury(II) Oxide, Triphenylphosphine in the presence of Diethyl Azaodicarboxylate, or mercury(II) benzamide. A synthetic method of dimerizing p-tolyl isocyanate has been reported.

Precautions

Harmful inhalation, ingestion, skin absorption, and exposure causes strong eye and lung irritation. The solid is light- and moisture-sensitive and should be refrigerated in dark, well-sealed containers under an inert atmosphere. It should be used in a fume hood.

1,3-DI-P-TOLYLCARBODIIMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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726-42-1, 1,3-DI-P-TOLYLCARBODIIMIDERelated Search:


  • di-p-tolylcarbodiimide
  • DI-PARA-TOLYLCARBODIIMIDE
  • DI-P-TOLY CARBODIIMIDE
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  • N,N'-DI-P-TOLYLCARBODIMIDE
  • 1,3-Bis(p-tolyl)carbodiimide
  • Bis(4-methylphenyl)carbodiimide
  • Bis(p-tolyl)carbodiimide
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