8-FLUOROQUINOLINE

Product Name: 8-FLUOROQUINOLINE
CAS No.: 394-68-3
Chemical Name: 8-FLUOROQUINOLINE
Synonyms: 8-Fluoroquinoine;8-FLUOROQUINOLINE;8-fluoro-quinolin;Quinoline, 8-fluoro-;8-FLUOROQUINOLINE ISO 9001：2015 REACH
CBNumber: CB8359728
Molecular Formula: C9H6FN
Formula Weight: 147.15
MOL File: 394-68-3.mol

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8-FLUOROQUINOLINE Property

Boiling point:: 148 °C(Press: 30 Torr)
Density: 1.215 g/cm3(Temp: 25 °C)
refractive index: 1.60
storage temp.: Inert atmosphere,Room Temperature
form: clear liquid
pka: 1.93±0.17(Predicted)
color: Colorless to Light yellow to Light orange
InChI: InChI=1S/C9H6FN/c10-8-5-1-3-7-4-2-6-11-9(7)8/h1-6H
InChIKey: RNAAXKYOTPSFGV-UHFFFAOYSA-N
SMILES: N1C2C(=CC=CC=2F)C=CC=1
CAS DataBase Reference: 394-68-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
HS Code: 2933499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

TCI Chemical

Product number: F1185
Product name: 8-Fluoroquinoline
Packaging: 1G
Price: $36
Updated: 2025/07/31

TCI Chemical

Product number: F1185
Product name: 8-Fluoroquinoline
Packaging: 5G
Price: $108
Updated: 2025/07/31

TRC

Product number: F596860
Product name: 8-Fluoroquinoline
Packaging: 500mg
Price: $65
Updated: 2021/12/16

TRC

Product number: F596860
Product name: 8-Fluoroquinoline
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: F596860
Product name: 8-Fluoroquinoline
Packaging: 250mg
Price: $55
Updated: 2021/12/16

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8-FLUOROQUINOLINE Chemical Properties,Usage,Production

Chemical Properties

Pale yellow solid

Synthesis

348-54-9

56-81-5

394-68-3

1. 85% sulfuric acid (623 g) was added to a 1 L reaction flask and o-fluoroaniline (133 g, 1.2 mol) was added slowly and dropwise. 2. The reaction mixture was heated to 130 °C and stirred at this temperature for 2 hours. 3. maintaining the reaction temperature at 130 °C, glycerol (121 g, 1.3 mol) and potassium iodide (3 g) were added slowly dropwise to the mixture. 4. After completion of the dropwise addition, the reaction mixture was continued to be stirred at 130 °C for 18 hours. 5. The reaction solution was cooled to room temperature and then slowly poured into ice water for quenching. 6. After quenching, aqueous sodium hydroxide solution was added dropwise to adjust the pH to 8-9. 7. Extraction was carried out with methyl tert-butyl ether, the oil layer was separated and concentrated. 8. The concentrate was distilled under high vacuum by means of a filled distillation column to give 8-fluoroquinoline (146 g) of high purity. 9. The yield was 83% and gas chromatographic analysis showed a purity of 99.7%.

References

[1] Patent: CN107698503, 2018, A. Location in patent: Paragraph 0061-0072
[2] Biological and Pharmaceutical Bulletin, 1997, vol. 20, # 6, p. 646 - 650

8-FLUOROQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-FLUOROQUINOLINE Suppliers

Americas 1 China 145 Europe 1 Germany 4 India 7 Italy 1 Japan 1 United Kingdom 5 United States 12 Global 177

Shanghai Kuanglin Tech LTD Co

Tel: 13701867986
Email: 13701867986@163.com
Country: China
ProdList: 100
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
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ZEROSCHEM.CO.,LTD.

Tel: 10-61256048 13810278579
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
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View Lastest Price from 8-FLUOROQUINOLINE manufacturers

Hebei Mingeng Biotechnology Co., Ltd

Product: 8-Fluoroquinoline 394-68-3
Price: US $200.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg/Month
Release date: 2022-11-21

Zhuozhou Wenxi import and Export Co., Ltd

Product: 8-FLUOROQUINOLINE 394-68-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Career Henan Chemical Co

Product: 8-FLUOROQUINOLINE 394-68-3
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: ask
Release date: 2018-12-20

394-68-3, 8-FLUOROQUINOLINERelated Search:

ethyl 8-fluoroquinoline-3-carboxylate 8-FLUOROQUINOLINE-3-CARBOXYLIC ACID 8-Fluoroquinolin-2(1H)-one 8-FLUOROQUINOLINE-2-CARBOXYLIC ACID 4-CHLORO-8-FLUOROQUINOLINE 4-HYDROXY-8-FLUOROQUINOLINE 4-CHLORO-6,8-DIFLUOROQUINOLINE 8-FLUORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE 8-FLUORO-2-METHYL-4-QUINOLINOL ETHYL 4-CHLORO-8-FLUOROQUINOLINE-3-CARBOXYLATE 4-CHLORO-8-FLUORO-2-METHYLQUINOLINE ETHYL 4-CHLORO-6,8-DIFLUOROQUINOLINE-3-CARBOXYLATE 8-FLUORO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID 2-CHLORO-4-FLUOROQUINOLINE 2-METHYL-7-FLUOROQUINOLINE 7-FLUOROQUINOLINE-4-OL,4-Hydroxy-7-fluoroquinoline ETHYL 4-CHLORO-6-FLUOROQUINOLINE-3-CARBOXYLATE 1-ETHYL-6,7,8-TRIFLUORO-1,4-DIHYDRO-4-FLUOROQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

8-fluoro-quinolin

8-FLUOROQUINOLINE

Quinoline, 8-fluoro-

8-Fluoroquinoine

8-FLUOROQUINOLINE ISO 9001：2015 REACH

394-68-3

Quinolines, Quinazolines and derivatives