ChemicalBook > CAS DataBase List > Androstenedione

Androstenedione

Biological Metabolism

Product Name: Androstenedione
CAS No.: 63-05-8
Chemical Name: Androstenedione
Synonyms: 4-AD;4-ANDROSTENEDIONE;4-ANDROSTENE-3,17-DIONE;ANDROSTENDIONE;ANDROSTA-4-ENE-3,17-DIONE;Androstenedione (CRM);skf2170;ANDROTEX;SKF 2170;Fecundin
CBNumber: CB8365581
Molecular Formula: C19H26O2
Formula Weight: 286.41
MOL File: 63-05-8.mol

Less

Androstenedione Property

Melting point:: 170-171 °C(lit.)
Boiling point:: 368.77°C (rough estimate)
alpha: D30 +199° (in chloroform)
Density: 1.0655 (rough estimate)
refractive index: 1.4709 (estimate)
Flash point:: 2℃
storage temp.: Controlled Substance, -20°C Freezer
solubility: Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Sparingly)
form: Solid
color: Dimorphous: Needles from acetone, or crystalsfrom hexane
Water Solubility: 57.28mg/L(25 ºC)
Merck: 13,643
InChIKey: AEMFNILZOJDQLW-QAGGRKNESA-N
CAS DataBase Reference: 63-05-8(CAS DataBase Reference)
NIST Chemistry Reference: Androst-4-ene-3,17-dione(63-05-8)
EPA Substance Registry System: 4-Androstenedione (63-05-8)

Less

Safety

Hazard Codes: Xn,T,F
Risk Statements: 40-64-52-22-61-60-36-20/21/22-11
Safety Statements: 22-24/25-36-45-36/37-53-26-16
RIDADR: UN 1648 3 / PGII
WGK Germany: 3
RTECS: BV8150000
HS Code: 29372900
Hazardous Substances Data: 63-05-8(Hazardous Substances Data)

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2364
Product name: 4-Androstenedione
Purity: ≥98% (HPLC)
Packaging: 250MG
Price: $63
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML2364
Product name: 4-Androstenedione
Purity: ≥98% (HPLC)
Packaging: 500MG
Price: $121
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHR8811
Product name: Testosterone Related Compound A
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 50 mg
Price: $517
Updated: 2025/07/31

Sigma-Aldrich

Product number: PHL89562
Product name: Androstenedione
Purity: phyproof? Reference Substance
Packaging: 100MG
Price: $179
Updated: 2025/07/31

Sigma-Aldrich

Product number: A-075
Product name: Androstenedione solution
Purity: 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $52.4
Updated: 2025/07/31

Less

Androstenedione Chemical Properties,Usage,Production

Biological Metabolism

The in vitro perfusion of the human placental lobule with 7-ethoxycoumarin gives 7-hydroxycoumarin, and perfusion with androstenedione gives the conversion products, estrone, estradiol, and testosterone. The human placenta has only a limited capacity for the metabolism of xenobiotics.

Description

Androstenedione (CRM) (Item No. ISO60161) is a certified reference material categorized as an anabolic androgenic steroid. Androstenedione is a precursor of testosterone (Item Nos. ISO60154 | ISO00154 | 15645) and estrone . Androstenedione is regulated as a Schedule III compound in the United States. Androstenedione (CRM) (Item No. ISO60161) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

Chemical Properties

White to Off-White Solid

Uses

Testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic sterid)

Definition

ChEBI: A 3-oxo Delta4-steroid that is androst-4-ene substituted by oxo groups at positions 3 and 17. It is a steroid hormone synthesized in the adrenal glands and gonads.

Safety Profile

An experimental teratogen. Otherexperimental reproductive effects. Questionablecarcinogen with experimental tumorigenic data. Whenheated to decomposition it emits acrid smoke andirritating fumes.

Purification Methods

Crystallise the dione from hexane. It is soluble in *C6H6, CHCl3 and EtOH. It has max at 239nm. It is a precursor of estrone or testosterone and has androgenic activity. [Ruzicka & Wettstein Helv Chim Acta 18 980 1935, Beilstein 7 III 3636, 7 IV 2381.]

Toxics Screening Level

The initial threshold screening level (ITSL) for androstenedione is 17 μg/m3 based on an annual averaging time.

References

[1] F. CHEN. Partial agonist/antagonist properties of androstenedione and 4-androsten-3β,17β-diol[J]. Journal of Steroid Biochemistry and Molecular Biology, 2004, 91 4: Pages 247-257. DOI: 10.1016/j.jsbmb.2004.04.009
[2] Toxicology and carcinogenesis studies of androstenedione (CAS No. 63-05-8) in F344/N rats and B6C3F1 mice (gavage studies).[J]. National Toxicology Program technical report series, 2010, 560: 1, 7-31,33-171 passim.
[3] OSTOJI? S, CALLEJA-GONZáLEZ J, STOJANOVI? M. Steroid Prohormones: Effects on Body Composition in Athletes[C]. 2011: 0. DOI: 10.5772/28543

Androstenedione Preparation Products And Raw materials

Raw materials

Preparation Products

Spironolactone

Less

Androstenedione Suppliers

Canada 2 China 285 Europe 1 France 1 Germany 3 India 7 Japan 1 Switzerland 1 United Kingdom 7 United States 19 Global 327

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Wuhan Wei Shunda Technology Development Co., Ltd.

Tel: 86-027-88774375
Fax: 86-027-88416321
Email: mwmwhot@163.com
Country: China
ProdList: 233
Advantage: 65

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5645
Advantage: 65

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-83725681-603
Fax: +86 755 28094224
Country: China
ProdList: 4496
Advantage: 50

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

China Nobel Chem Co., Limited

Tel: +86(0)21 60484900
Fax: +86(0)21 60484900
Country: China
ProdList: 764
Advantage: 50

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

Zouping Mingxing Chemical Co.,Ltd.

Tel: 86-13605431940 13605431940
Fax: 0086-0543-2240079
Email: zpmxchemical@126.com
Country: China
ProdList: 1490
Advantage: 62

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3921
Advantage: 50

Wuhan DKY Technology Co.,Ltd.

Tel: 027-27-81302488 15972195220
Fax: 027-81302088
Email: info@dkybpc.com
Country: China
ProdList: 1758
Advantage: 58

Hubei XinyuanShun Chemical Co., Ltd.

Tel: 13971561712, 13995564702, 027-50664929
Fax: 027-50664927
Email: hbeixys2001@163.com
Country: China
ProdList: 3120
Advantage: 55

Shanghai Meishui Chemical Technology Co., Ltd

Tel: 021-60549325 18616193163
Fax: 021-33250306
Country: China
ProdList: 4526
Advantage: 56

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Shanghai Union Resource Chemistry Co., Ltd

Tel: 021-50454025 18930054025
Fax: 021-50454025
Country: China
ProdList: 103
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Wuhan Dahua Pharmaceutical Co., Ltd.

Tel: 027-59262863 13277907145 3091977954
Fax: 027-59420980
Country: China
ProdList: 4942
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 14912
Advantage: 59

Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd.

Tel: 027-59420981,18702770802
Fax: 027-83322098
Country: China
ProdList: 1975
Advantage: 50

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

Chizhou Kailong Import and Export Trade Co., Ltd.

Tel
Fax: -
Email: xg01_gj@163.com
Country: China
ProdList: 9484
Advantage: 50

Changsha Jing Kang New Material Technology Co., Ltd.

Tel: 0733-0731-85118349 18874718518
Fax: 0731-85118349
Email: 877634463@qq.com
Country: China
ProdList: 1864
Advantage: 50

Taizhou shengyu chemical co.,ltd

Tel: 0576-81816116 18969655221
Fax: 576-81816116
Email: Shengyu@shengyuchemical.com
Country: China
ProdList: 130
Advantage: 65

Struchem Co., Ltd.

Tel: 0512-63009836 18994340901
Fax: 0512-63006936
Email: helen@struchem.com
Country: China
ProdList: 3981
Advantage: 60

Wuhan Senwayer Century Chemical Co.,Ltd

Tel: 027-86652399 13627115097;
Fax: 86-27-59707018
Email: sales@senwayer.com
Country: China
ProdList: 266
Advantage: 55

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-58088081 Q2635253576
Fax: QQ3382968513
Email: hailey@shsendpharm.com
Country: China
ProdList: 2081
Advantage: 55

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 028-88469284 18000562381
Email: rzbtsj@163.com
Country: China
ProdList: 9951
Advantage: 56

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Jinan Putubio Tech Co., Ltd.

Tel: +86 (531) 8099-2215
Fax: +86 (531) 8099-2215
Email: putubio@outlook.com
Country: China
ProdList: 1261
Advantage: 55

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9941
Advantage: 58

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

Raw material medicin reagent co.,Ltd

Tel
Email: sales@njromanme.com
Country: China
ProdList: 4529
Advantage: 58

Chengdu Huachun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Shanghai ChengShao Biological Technology Co., Ltd.

Tel: 021-61847300 13341622919
Fax: 021-61847300
Email: shcss01@163.com
Country: China
ProdList: 4808
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29760
Advantage: 68

Shenzhen Simeiquan Biotechnology Co. Ltd

Tel: 18126413629 0755-23311925 2355327053
Fax: 0755-23311925
Email: abel@ycgmp.com
Country: China
ProdList: 5113
Advantage: 58

Shandong JunRui Pharmaceutical Co., Ltd.

Tel: 0539-5636807 15318528770
Fax: 0539-5636807
Email: ffeng813@163.com
Country: China
ProdList: 254
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shenzhen Sendi Biological Technology Co., Ltd.

Tel: 18124570582 TEL：0755-23574479 2355327139
Fax: 0755-23229476 QQ: 2355327139
Email: siliao02@yccreate.com
Country: China
ProdList: 6116
Advantage: 58

Wuhan Landed Scientific Ltd.

Tel: 027-88739577 18163556322
Fax: 027-88739578
Email: sales@landed.com.cn
Country: China
ProdList: 59
Advantage: 55

Guangzhou Kafen Biotech Co.,Ltd

Tel: 18029243487 2355327168
Fax: 020-31121510
Email: gy@yccreate.com
Country: China
ProdList: 4749
Advantage: 55

Less

View Lastest Price from Androstenedione manufacturers

Wuhan Biocar Pharmacy CO.,Ltd.

Product: 4-Androstenedione 63-05-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5000KG
Release date: 2025-02-26

Hebei Yanxi Chemical Co., Ltd.

Product: Androstenedione 63-05-8
Price: US $40.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-09-12

Wuhan Xinhao Biotechnology Co., Ltd

Product: Androst-4-ene-3,17-dione 63-05-8
Price: US $10.00-100.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100 tons
Release date: 2024-01-17

63-05-8, AndrostenedioneRelated Search:

Androstenedione-3,17-Dione 6-METHYLENEANDROST-4-ENE-3,17-DIONE 2,2-Dimethyl-1,3-propanediol 1-ChloroMethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate) 1-Bromopentane Bromoacetonitrile PotassiuM triMethylacetate, 95% ZINC-COPPER COUPLE Exemestane Impurity 13 Exemestane impurity B -F 17-Beta-Hydroxy Exemestane Epoxide Androstenediol Exemestane 6-Oxo Boldione ExeMestane Related CoMpound Exemestane Impurity 1 Exemestane Impurity 11 androstane-3,6,17-triol

3,17-Dioxoandrost-4-Ene

Androstenedione (CRM)

Testosterone EP Impurity A

4-Androstene-3

4-androsten-3,17-dione (4-AD)

4-Androstene-3,17-dione Solution, 100ppm

Androstenedione solution

4-androstene-3,17-dione(4-AD)

Androstenedione solution,100ppm

(8R,9S,10R,13S,14S)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione

(8R,9S,10R,13S,14S)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-quinone

(8R,9S,10R,13S,14S)-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione

4-AD

(+)-4-ANDROSTEN-3,17-DIONE

4-ANDROSTEN-3,17-DIONE

4-ANDROSTENE-3,17-DIONE

4-ANDROSTENEDIONE

ANDROSTENDIONE

ANDROTEX

ANDROSTENEDIONE

ANDROST-4-ENE-3, 17-DIONE

ANDROST-4-ENE-3,17-DIONE, 10,13-DIMETHYL-2,6,7,8,9,11,12,14,15,16-DECAHYDRO-1H-CYCLOPENTA[A]PHENANTHRENE-3,17-DIONE

ANDROSTA-4-ENE-3,17-DIONE

delta-(sup4)-Androsten-3,17-dione

delta(Sup4)-Androstene-3,17-dione

delta4-androsten-3,17-dione

delta-4-androstenedione

SKF 2170

skf2170

(8R,9S,10R,13S,14S)-10,13-DIMETHYL-1,6,7,8,9,10,11,12,13,14,15,16-DODECAHYDRO-2H-CYCLOPENTA[A]PHENANTHRENE-3,17-DIONE

3,17-DIOXO-4-ANDROSTENE

Androsten-3,17-dione

Androstenedione (JAN)

Androstenedione 4-AD

Androstenedione 10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]ph 10,13-Dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-dione

Testosterone Impurity 1(Testosterone EP Impurity A)

10,13-DIMETHYL-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHRENE-3,17-DIONE

4-Androstenedione(4AD)

17-Ketotestosterone

Fecundin

NSC 9563

ndrostenedione

10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione

ANDROSTENEDIONE(SH)

4-ANDROSTENEDIONE(ANDROSTENEDIONE)

DELTA-ANDROSTEN-3,17-DIONE

DELTA4-ANDROSTENE-3,17-DIONE

4-ANDROSTENE-3,1,7-DIONE, FROM DIOSCOREA OPPOSITA THUNB.99%(HPLC)

4-ANDROSTENE-3,17-DIONE 98.5+%

4-ANDROSTENEDIONE 99% MIN

(4-AD)4-ANDROSTENEDIONE

4-ANDROSTENEDIONE (4-ANDROSTENE-3,17-DIONE)

Androst-4-endione

4-androstenedione(biological method)4-AD

7-Oxo-Dehydroepiandrosterone(7-OXO-DHEA)

Androst-4-ene-3,17-dione (Androsten

Androstenedione,HPLC≥98%

Androstenedione standard solution, 100ppm