3,3-PENTAMETHYLENE-2-PYRROLIDINONE

Product Name: 3,3-PENTAMETHYLENE-2-PYRROLIDINONE
CAS No.: 1005-85-2
Chemical Name: 3,3-PENTAMETHYLENE-2-PYRROLIDINONE
Synonyms: CAI;Carbonic anhydrase 1;Carbonate dehydratase I;2-Azaspiro[4.5]decan-1-one;3-AZASPIRO[5.5]UNDECANE-2,4-DIONE;3,3-PENTAMETHYLENE-2-PYRROLIDINONE
CBNumber: CB8376677
Molecular Formula: C9H15NO
Formula Weight: 153.22
MOL File: 1005-85-2.mol

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3,3-PENTAMETHYLENE-2-PYRROLIDINONE Property

Melting point:: 110 °C
Boiling point:: 148-152 °C(Press: 1-2 Torr)
Density: 1.05±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 16.27±0.20(Predicted)
Appearance: White to off-white Solid
CAS DataBase Reference: 1005-85-2(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-W021583
Product name: 2-Azaspiro[4.5]decan-1-one
Purity: >98.0%
Packaging: 100mg
Price: $79
Updated: 2021/12/16

ChemScene

Product number: CS-W021583
Product name: 2-Azaspiro[4.5]decan-1-one
Purity: >98.0%
Packaging: 250mg
Price: $128
Updated: 2021/12/16

AK Scientific

Product number: 2636DC
Product name: 2-Azaspiro[4.5]decan-1-one
Packaging: 250mg
Price: $231
Updated: 2021/12/16

ChemScene

Product number: CS-W021583
Product name: 2-Azaspiro[4.5]decan-1-one
Purity: >98.0%
Packaging: 1g
Price: $348
Updated: 2021/12/16

AK Scientific

Product number: CS-W021583
Product name: 2-Azaspiro[4.5]decan-1-one
Packaging: 1g
Price: $348
Updated: 2021/12/16

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3,3-PENTAMETHYLENE-2-PYRROLIDINONE Chemical Properties,Usage,Production

Synthesis

956122-75-1

1005-85-2

A reaction mixture was prepared from methyl 1-cyanomethyl-cyclohexanecarboxylate (4.28 g, 23.6 mmol) and cobalt(II) chloride hexahydrate (2.81 g, 11.8 mmol) in a solvent mixture of THF (80 mL) and water (40 mL) at 0 °C. Subsequently, sodium borohydride (4.47 g, 0.118 mol) was added in batches and the reaction mixture was slowly warmed to room temperature and stirred under nitrogen protection for 48 hours. Upon completion of the reaction, the reaction was quenched by the addition of 28% ammonium hydroxide solution (3.1 mL) and filtered through Hyflo. The filtrate was concentrated under reduced pressure and the residue was diluted with minimal amounts of water and brine and then extracted three times with 3:1 chloroisopropanol. The organic layers were combined, dried over anhydrous sodium sulfate and the solvent was removed under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography using a gradient elution with a dichloromethane solution of 0 to 10% methanol to give 2-azaspiro[4.5]decan-1-one 1.95 g (54% yield). Thin layer chromatography (TLC) Rf value was 0.46 (unfolding agent: 9/1 dichloromethane/methanol). Mass spectrometry (MS) showed a molecular ion peak m/z: 154 (M+).

References

[1] Patent: WO2007/127763, 2007, A2. Location in patent: Page/Page column 33; 40

3,3-PENTAMETHYLENE-2-PYRROLIDINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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3,3-PENTAMETHYLENE-2-PYRROLIDINONE Suppliers

China 45 India 2 Japan 1 United Kingdom 3 United States 17 Global 68

Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

Tel: 21-57721279
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Tel: +86057186818502 13588463833
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BePharm Ltd

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Cool Pharm, Ltd

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Hangzhou Huarong Pharm Co., Ltd.

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View Lastest Price from 3,3-PENTAMETHYLENE-2-PYRROLIDINONE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3,3-PENTAMETHYLENE-2-PYRROLIDINONE 1005-85-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000KG
Release date: 2024-07-30

Career Henan Chemical Co

Product: 3,3-PENTAMETHYLENE-2-PYRROLIDINONE 1005-85-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 85.0-99.8%
Supply Ability: 200kgs
Release date: 2020-01-16

1005-85-2, 3,3-PENTAMETHYLENE-2-PYRROLIDINONERelated Search:

4,4-PENTAMETHYLENE-2-PYRROLIDINONE 4,4-PENTAMETHYLENE-2-PYRROLIDINONE TIMTEC-BB SBB001021 2-(3-DIETHYLAMINO-PROPYL)-8,8-DIPROPYL-2-AZA-SPIRO[4.5]DECANE-1,3-DIONE 3,3-PENTAMETHYLENE-2-PYRROLIDINONE 2-AZASPIRO[4,5]DECANE 2-AZASPIRO[4.5]DECANE-1,3-DIONE

3,3-PENTAMETHYLENE-2-PYRROLIDINONE

3-AZASPIRO[5.5]UNDECANE-2,4-DIONE

CAI

2-Azaspiro[4.5]decan-1-one

Carbonate dehydratase I

Carbonic anhydrase 1

1005-85-2

1133-32-1

C9H15NO