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ECHINOCYSTIC ACID

Product Name
ECHINOCYSTIC ACID
CAS No.
510-30-5
Chemical Name
ECHINOCYSTIC ACID
Synonyms
(3B2;16B1;(3u0003B2;16u0003B1;Echinocystic;Albizziagenin;Echicystic acid;ECHINOCYSTIC ACID;ECHINOCYSTIC ACID(SH);ECHINOCYSTIC ACID hplc
CBNumber
CB8379128
Molecular Formula
C30H48O4
Formula Weight
472.7
MOL File
510-30-5.mol
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ECHINOCYSTIC ACID Property

Melting point:
299-300°C
Boiling point:
585.0±50.0 °C(Predicted)
Density 
1.14
storage temp. 
2-8°C
solubility 
DMF:30.0(Max Conc. mg/mL);63.46(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.33(Max Conc. mg/mL);0.7(Max Conc. mM)
form 
powder
pka
4.43±0.70(Predicted)
color 
White
LogP
7.580 (est)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00505
Product name
Echinocystic acid
Purity
≥95%
Packaging
5MG
Price
$91.6
Updated
2022/05/15
Cayman Chemical
Product number
27476
Product name
Echinocystic Acid
Packaging
10mg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
27476
Product name
Echinocystic Acid
Packaging
100mg
Price
$879
Updated
2024/03/01
Cayman Chemical
Product number
27476
Product name
Echinocystic Acid
Packaging
50mg
Price
$467
Updated
2024/03/01
Cayman Chemical
Product number
27476
Product name
Echinocystic Acid
Packaging
250mg
Price
$1933
Updated
2024/03/01
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ECHINOCYSTIC ACID Chemical Properties,Usage,Production

Description

Echinocystic acid is a triterpene that has been found in G. sinensis and has diverse biological activities. It induces nuclear translocation of the glucocorticoid receptor (GR) and reduces TNF-α-induced NF-κB signaling in HEK293 cells overexpressing GFP-GR. Echinocystic acid (12.5, 25, and 50 μM) suppresses RANKL-induced NF-κB activation, ERK phosphorylation, and osteoclastogenesis in mouse bone marrow macrophages (BMMs). It induces neurite outgrowth in Neuro2A cells in a concentration-dependent manner, an effect that can be blocked by the JNK inhibitor SP 600125 . In vivo, echinocystic acid (10 mg/kg per day) decreases escape latency in the Morris water maze and increases the length of neurite processes in the hippocampus of aged mice. Topical administration of echinocystic acid reduces expression of COX-2, inducible nitric oxide synthase (iNOS), TNF-α, and IL-1β and ear edema induced by phorbol 12-myristate 13-acetate (TPA; ) in a mouse model of dermatitis. Echinocystic acid also recovers reductions in femoral bone mineral density and trabecular thickness and number in a rat model of ovariectomy-induced osteoporosis.

Uses

Echinocystic Acid is a potential entry inhibitor for the HCV infection.

Definition

ChEBI: Echinocystic acid is a triterpenoid.

ECHINOCYSTIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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ECHINOCYSTIC ACID Suppliers

Nanjing Spring & Autumn Biological Engineering Co., Ltd.
Tel
025-84430028 13815430202
Email
sale02@cqherb.com
Country
China
ProdList
279
Advantage
59
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6013
Advantage
61
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5658
Advantage
65
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4941
Advantage
60
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
Shanghai Winherb Medical Technology Co., Ltd.
Tel
400-1865138 13341702378
Fax
QQ:190129269
Email
190129269@qq.com
Country
China
ProdList
1010
Advantage
58
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
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View Lastest Price from ECHINOCYSTIC ACID manufacturers

Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
ECHINOCYSTIC ACID 510-30-5
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
≥98%
Supply Ability
20tons
Release date
2024-01-03
Hebei Mojin Biotechnology Co., Ltd
Product
ECHINOCYSTIC ACID 510-30-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-10-16
Hebei Guanlang Biotechnology Co., Ltd.
Product
ECHINOCYSTIC ACID 510-30-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2023-03-24

510-30-5, ECHINOCYSTIC ACIDRelated Search:


  • ECHINOCYSTIC ACID
  • 3-B,16-A-DIHYDROXYOLEAN-12-EN-28-OIC ACID
  • 3BETA,16ALPHA-DIHYDROXY-OLEAN-12-EN-28-OIC ACID
  • (3beta,16alpha)-3,16-dihydroxyolean-12-en-28-oic acid
  • Echinocystic
  • ECHINOCYSTIC ACID(SH)
  • ECHINOCYSTIC ACID hplc
  • Echinocystic acid 510-30-5
  • (4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bS)-5,10-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
  • ECHINOCYSTIC ACID WITH HPLC
  • 3β,16α-Dihydroxy-5α-oleana-12-ene-28-oic acid
  • 3β,16α-Dihydroxyolean-12-en-28-oic acid
  • Echicystic acid
  • Albizziagenin
  • Echinocystic acid, 98%, from Hedera Linn.
  • ECHINOCYSTIC ACID USP/EP/BP
  • (3B2
  • (3u0003B2
  • )-3,16-dihydroxyolean-12-en-28-oic acid
  • 16B1
  • 16u0003B1
  • Echinocystic acid (6CI)
  • Olean-12-en-28-oic acid, 3,16-dihydroxy-, (3β,16α)-
  • 510-30-5
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Tri-Terpenoids
  • Inhibitors