ChemicalBook > CAS DataBase List > 5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINE

5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINE

Product Name
5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINE
CAS No.
65373-29-7
Chemical Name
5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINE
Synonyms
MS21570;ZERENEX E/5111275;MS21570, 10 mM in DMSO;Inhibitor,MS 21570,inhibit,MS21570,MS-21570;5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINE;N-(5-benzylsulfanyl-[1,3,4]thiadiazol-2-yl)-methylamine;N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazadiazol-2-amine;1,3,4-thiadiazol-2-amine, N-methyl-5-[(phenylmethyl)thio]-
CBNumber
CB8380663
Molecular Formula
C10H11N3S2
Formula Weight
237.34
MOL File
Mol file
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5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINE Property

Boiling point:
389.6±35.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 125 mg/mL (526.67 mM)
form 
Solid
pka
2.67±0.10(Predicted)
color 
White to off-white
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Safety

HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2593
Product name
MS0021570
Purity
≥98% (HPLC)
Packaging
5mg
Price
$97.7
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2593
Product name
MS0021570
Purity
≥98% (HPLC)
Packaging
25mg
Price
$395
Updated
2024/03/01
Tocris
Product number
6298
Product name
MS21570
Purity
≥98%(HPLC)
Packaging
10
Price
$117
Updated
2021/12/16
Tocris
Product number
6298
Product name
MS21570
Purity
≥98%(HPLC)
Packaging
50
Price
$488
Updated
2021/12/16
Usbiological
Product number
456667
Product name
MS 21570
Packaging
1mg
Price
$326
Updated
2021/12/16
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5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINE Chemical Properties,Usage,Production

Uses

MS 21570, is a GPR171 antagonist. It reduces anxiety-like behavior and fear conditioning in mice.

Biological Activity

MS0021570 is a potent antagonist of GPR171, a G protein-coupled receptor of BigLEN (b-LEN), which is a neuropeptide derived from proSAAS and involved in regulation of feeding. MS0021570 had a IC50 value of 220 nM. It was shown to block inceases in food intake and to reduce anxiety-like behavior and fear conditioning in mice.

storage

Store at -20°C

5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINE Suppliers

China 26 United Kingdom 3 United States 9 Global 38
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
Zerenex Molecular Limited
Tel
--
Fax
--
Email
sales@zerenex-molecular.com
Country
United Kingdom
ProdList
6204
Advantage
47

65373-29-7, 5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINERelated Search:

N-Methyldiethanolamine N-Methylbenzylamine

  • 5-(BENZYLTHIO)-N-METHYL-1,3,4-THIADIAZOL-2-AMINE
  • MS21570
  • ZERENEX E/5111275
  • 1,3,4-thiadiazol-2-amine, N-methyl-5-[(phenylmethyl)thio]-
  • N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazadiazol-2-amine
  • N-(5-benzylsulfanyl-[1,3,4]thiadiazol-2-yl)-methylamine
  • Inhibitor,MS 21570,inhibit,MS21570,MS-21570
  • MS21570, 10 mM in DMSO
  • 65373-29-7