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Lopinavir-d8

Product Name
Lopinavir-d8
CAS No.
1322625-54-6
Chemical Name
Lopinavir-d8
Synonyms
LOPINAVIR-D8;2,3,4,4,4-pentadeuterio-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide
CBNumber
CB83814039
Molecular Formula
C37H40D8N4O5
Formula Weight
636.850114224
MOL File
1322625-54-6.mol
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Lopinavir-d8 Property

Melting point:
>96°C (dec.)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
Off-White to Pale Beige
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
25284
Product name
Lopinavir-d8
Purity
≥99% deuterated forms (d1-d8)
Packaging
1mg
Price
$456
Updated
2024/03/01
Usbiological
Product number
L3420-31
Product name
Lopinavir-d8
Packaging
1mg
Price
$566
Updated
2021/12/16
TRC
Product number
L469482
Product name
Lopinavir-d8
Packaging
10mg
Price
$2080
Updated
2021/12/16
AK Scientific
Product number
5704DV
Product name
2,3,4,4,4-Pentadeuterio-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide
Packaging
1mg
Price
$606
Updated
2021/12/16
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Lopinavir-d8 Chemical Properties,Usage,Production

Description

Lopinavir-d8 is intended for use as an internal standard for the quantification of lopinavir by GC- or LC-MS. Lopinavir is a potent HIV-1 protease inhibitor (Ki = 1.3 pM for wild-type enzyme). It inhibits the replication of clinical isolates of HIV-1 (EC50s = 5-52 nM). Lopinavir reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; EC50s = 26.63 and 26.10 μM, respectively). It reduces lung and kidney viral load, bronchointerstitial pneumonia, and pulmonary inflammatory cell infiltration in a marmoset model of Middle East respiratory syndrome coronavirus (MERS-CoV) infection when administered in combination with ritonavir .

Uses

A labelled selective HIV protease inhibitor. An analogue of Ritonavir. Antiviral. It is a COVID19-related research product.

Lopinavir-d8 Preparation Products And Raw materials

Raw materials

Preparation Products

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Lopinavir-d8 Suppliers

China 24 India 2 United States 3 Global 29
Artis Biotech Co. Ltd.
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0575-18780151478 18582380095
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0575-89298961
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sales@artisbio.com
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China
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
Fax
021-65675885
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info@efebio.com
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China
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9806
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Nanjing Haolv Biotechnology Co.,Ltd
Tel
025-84622273 17361806303
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3004208264@qq.com
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China
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3021
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
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sales@chemegen.com
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China
ProdList
11218
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Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
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info@synzest.com
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China
ProdList
9286
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Energy Chemical
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021-58432009 400-005-6266
Fax
021-58436166
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marketing1@energy-chemical.com
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China
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44807
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Changzhou Bojia Biomedical Technology Co., Ltd.
Tel
2122619822
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czbjpharma@126.com
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China
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LGC Science (Shanghai) Ltd.
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17717235263
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cindy.yang@lgcgroup.com
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China
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Shanghai Yiyan Biotechnology Co. , Ltd.
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021-69985186 13611928337
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China
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Shanghai isotope chemical co.,ltd
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021-021-51600108 13062666369
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Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd
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Hubei Moco Chemical Co., Ltd.
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TargetMol Chemicals Inc.
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15002134094
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Cato Research Chemicals Inc.
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Guangzhou CATO Research Chemicals Inc.
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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Xiamen Huijia Biological Technology Co., Ltd.
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Shanghai Ziqi Biological Technology Co., Ltd.
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Shanghai Yubo Biotechnology Co., Ltd.
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Boao Pike
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Beijing Shengke Boyuan Biotechnology Co., Ltd.
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Shanghai Hao Biological Technology Co., Ltd.
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Beijing Bolide Biotechnology Co., Ltd.
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1322625-54-6, Lopinavir-d8Related Search:


  • 2,3,4,4,4-pentadeuterio-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide
  • LOPINAVIR-D8
  • 1322625-54-6